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Chemical Structure| 2605-31-4 Chemical Structure| 2605-31-4

Structure of 2605-31-4

Chemical Structure| 2605-31-4

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Product Details of [ 2605-31-4 ]

CAS No. :2605-31-4
Formula : C7H4FNS
M.W : 153.18
SMILES Code : N#CSC1=CC=CC=C1F
MDL No. :MFCD15209720

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Application In Synthesis of [ 2605-31-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 2605-31-4 ]

[ 2605-31-4 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 78-67-1 ]
  • [ 14135-38-7 ]
  • [ 2605-31-4 ]
  • 2
  • [ 75-52-5 ]
  • [ 14135-38-7 ]
  • [ 2605-31-4 ]
YieldReaction ConditionsOperation in experiment
72% With iodine; potassium acetate; at 90℃; for 12h; General procedure: A 15-mL tube with a Teflon cap, equipped with a magnetic stirring bar, was charged with substrate 1 (0.20 mmol), iodine (0.40 mmol, 2.0 equiv), KOAc (1.0 mmol, 5.0 equiv) in MeNO2 (1mL) was then added sequentially. The tube was then capped and stirred at 90 °C for 12 h. the crude mixture was diluted with AcOEt, and washed with sat. aq Na2S2O3 solution (3 × 10 mL). The organic phase was dried (MgSO4), filtered through a Celite pad, and washed with AcOEt. The filtrate was concentrated in vacuo, and the resulting residue was purified by column chromatography,(hexane-EtOAc) to afford product 2.
 

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