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Chemical Structure| 27259-95-6 Chemical Structure| 27259-95-6

Structure of 27259-95-6

Chemical Structure| 27259-95-6

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Product Details of [ 27259-95-6 ]

CAS No. :27259-95-6
Formula : C7H16Cl2N2
M.W : 199.12
SMILES Code : NC1CC2(CC(N)C2)C1.[H]Cl.[H]Cl
MDL No. :MFCD11099887

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Application In Synthesis of [ 27259-95-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 27259-95-6 ]

[ 27259-95-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1239589-52-6 ]
  • [ 27259-95-6 ]
YieldReaction ConditionsOperation in experiment
57% With hydrogenchloride; In 1,4-dioxane; at 20℃; for 4h; (6-Amino-spiro[3.3]hept-2-yl)-carbamic acid tert-butyl ester 12 (100 mg, 0.442 mmol) was added to 4N HCl in dioxane (4 mL) and the resulting mixture was stirred at rt for 4 hrs. The resulting suspension was carefully filtered and washed with Et2O to afford 13 (50 mg, 57%) as the dihydrochloride salt and having the appearance of a white solid. 1H NMR (400 MHz, CDC13) delta 8.27 (s, 6H), 3.50-3.54 (m, 2H), 2.33-2.39 (m, 2H), 2.14-2.22 (m, 6H).
 

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