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[ CAS No. 276866-90-1 ]

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Cat. No.: {[proInfo.prAm]}
2D
Chemical Structure| 276866-90-1
Chemical Structure| 276866-90-1
Structure of 276866-90-1 *Storage: {[proInfo.prStorage]}

Quality Control of [ 276866-90-1 ]

Related Doc. of [ 276866-90-1 ]

SDS

Product Details of [ 276866-90-1 ]

CAS No. :276866-90-1MDL No. :MFCD09836681
Formula : C7H4ClIO Boiling Point : 304°C at 760 mmHg
Linear Structure Formula :-InChI Key :ARCZAXXTPLCEMP-UHFFFAOYSA-N
M.W :266.46Pubchem ID :11230916
Synonyms :

Computed Properties of [ 276866-90-1 ]

TPSA : 17.1 H-Bond Acceptor Count : 1
XLogP3 : - H-Bond Donor Count : 0
SP3 : 0.00 Rotatable Bond Count : 1

Safety of [ 276866-90-1 ]

Signal Word:WarningClassN/A
Precautionary Statements:P280-P305+P351+P338UN#:N/A
Hazard Statements:H302Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 276866-90-1 ]

  • Upstream synthesis route of [ 276866-90-1 ]
  • Downstream synthetic route of [ 276866-90-1 ]

[ 276866-90-1 ] Synthesis Path-Upstream   1~3

  • 1
  • [ 104-88-1 ]
  • [ 276866-90-1 ]
YieldReaction ConditionsOperation in experiment
40% at 20℃; for 1.50 h; Iodines (1.12 g, 4.4 mmol), and sodium iodates (400mg, 2.2 mmol) are put into the reaction container in which the sulfuric acid (30 ml) is contained and it 30 min.is stirred in at a room temperature. Thereafter, 4- chlorobenzaldehydes (1.40 g, 10.0 mmol) are additionally put and it is stirred in at a room temperature for 1 hour.The reaction mixture is poured into the iced water after the reaction completion and the then generated solidis filtered and until the product is neutralized it washeswith water. After the solid filtered was melted in ethanol it recrystallized and intended compound 1.06 gs (4.00 mmol, 40percent) were obtained.
Reference: [1] Bulletin of the Chemical Society of Japan, 2000, vol. 73, # 4, p. 951 - 956
[2] Tetrahedron, 2004, vol. 60, # 41, p. 9113 - 9119
[3] Synthesis, 2006, # 7, p. 1195 - 1199
[4] Patent: KR2016/149561, 2016, A. Location in patent: Paragraph 0125; 0126; 0127
[5] European Journal of Medicinal Chemistry, 2016, vol. 123, p. 180 - 190
  • 2
  • [ 104317-95-5 ]
  • [ 276866-90-1 ]
Reference: [1] Patent: WO2006/125511, 2006, A1. Location in patent: Page/Page column 56-57
  • 3
  • [ 16588-34-4 ]
  • [ 276866-90-1 ]
Reference: [1] Journal of the Chemical Society, 1927, p. 25
Historical Records

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