Home Cart Sign in  
Chemical Structure| 28917-41-1 Chemical Structure| 28917-41-1

Structure of 28917-41-1

Chemical Structure| 28917-41-1

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 28917-41-1 ]

CAS No. :28917-41-1
Formula : C8H8ClNO2
M.W : 185.61
SMILES Code : O=[N+](C1=CC=CC=C1CCCl)[O-]

Safety of [ 28917-41-1 ]

Application In Synthesis of [ 28917-41-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 28917-41-1 ]

[ 28917-41-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 15121-84-3 ]
  • [ 28917-41-1 ]
YieldReaction ConditionsOperation in experiment
With pyridine; thionyl chloride; In (2S)-N-methyl-1-phenylpropan-2-amine hydrate; chloroform; Example 1 2-(2-nitrophenyl)ethyl chloride 2.1 ml abs. pyridine and 21.62 g thionyl chloride (13.3 ml,. 0.18 mol) is added to 10.13 9 <strong>[15121-84-3]2-(2-nitrophenyl)ethanol</strong> (60 mmol) in 36 ml abs. toluene. After 2 h reflux, this is cooled and poured onto ice. The ice water is mixed with 50 ml chloroform and extracted 2* each with 50 ml chloroform. The combined organic phases are neutralized 2* each with 100 ml saturated bicarbonate solution. After drying with Na2 SO4, this is filtered and rotary evaporated. After distillation under high-vacuum, 9.7 9 (50 mmol,. 87percent) 2-(2-nitrophenyl)ethyl chloride is obtained as a yellow oil with a boiling point of 66 to 67° C. (0.001 mbar). TLC (silica gel): Rf =0.39 (PE/EE 9:1); 1 H-NMR (250 MHz, CDCl3): 8.00 (dd, 1H, arom. H, o to NO2), 7.59 (t, 1H, arom. H), 7.45 (m, 2H, arom. H), 3.85 (t, 2H, alpha-CH2), 3.38 (t, 2H, beta-CH2); UV (MeOH), lambda [nm] (1 g epsilon): 204 (4.06), [216 (3.78)], 256 (3.69).
 

Historical Records