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[ CAS No. 294-93-9 ] {[proInfo.proName]}

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Cat. No.: {[proInfo.prAm]}
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Chemical Structure| 294-93-9
Chemical Structure| 294-93-9
Structure of 294-93-9 * Storage: {[proInfo.prStorage]}
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Product Details of [ 294-93-9 ]

CAS No. :294-93-9 MDL No. :MFCD00005103
Formula : C8H16O4 Boiling Point : -
Linear Structure Formula :- InChI Key :XQQZRZQVBFHBHL-UHFFFAOYSA-N
M.W : 176.21 Pubchem ID :9269
Synonyms :

Safety of [ 294-93-9 ]

Signal Word:Danger Class:6.1
Precautionary Statements:P260-P280-P284-P301+P310-P310 UN#:2810
Hazard Statements:H301-H311-H330-H372 Packing Group:
GHS Pictogram:

Application In Synthesis of [ 294-93-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 294-93-9 ]

[ 294-93-9 ] Synthesis Path-Downstream   1~27

  • 1
  • [ 109-99-9 ]
  • [ 294-93-9 ]
  • [ 4158-64-9 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
58% With n-butyllithium In hexane for 0.166667h; ice bath;
58% With n-butyllithium In hexane for 0.5h;
  • 2
  • [ 1132-37-2 ]
  • [ 294-93-9 ]
  • C11H9(6)LiN2*C8H16O4 [ No CAS ]
  • 3
  • [ 294-93-9 ]
  • [ 7453-26-1 ]
  • [ 120547-14-0 ]
YieldReaction ConditionsOperation in experiment
50% With n-butyllithium In hexane for 1h; ice bath;
  • 4
  • [ 112-60-7 ]
  • [ 294-93-9 ]
YieldReaction ConditionsOperation in experiment
30% With cyanomethylenetributyl-phosphorane In benzene at 60℃; sealed vessel;
27% With p-toluenesulfonyl chloride; lithium tert-butoxide In <i>tert</i>-butyl alcohol Heating;
  • 5
  • [ 112-60-7 ]
  • [ 294-93-9 ]
  • [ 33089-37-1 ]
YieldReaction ConditionsOperation in experiment
1: 3% 2: 12% With sodium hydroxide; p-toluenesulfonyl chloride In 1,4-dioxane at 20℃;
  • 6
  • [ 112-60-7 ]
  • [ 294-93-9 ]
  • [ 33089-37-1 ]
  • [ 71092-59-6 ]
  • [ 71092-61-0 ]
YieldReaction ConditionsOperation in experiment
1: 23% 2: 11% 3: 4.3% 4: 1.4% With potassium hydroxide; p-toluenesulfonyl chloride In 1,4-dioxane at 65℃; Further byproducts given;
  • 7
  • [ 294-93-9 ]
  • [ 122-39-4 ]
  • [ 104619-75-2 ]
YieldReaction ConditionsOperation in experiment
35% With n-butyllithium In tetrahydrofuran; diethyl ether; hexane for 1h;
  • 8
  • [ 112-60-7 ]
  • [ 111-46-6 ]
  • [ 294-93-9 ]
  • [ 17455-13-9 ]
  • [ 33089-37-1 ]
YieldReaction ConditionsOperation in experiment
1: 3% 2: 23% With potassium hydroxide; p-toluenesulfonyl chloride In 1,4-dioxane at 60℃;
  • 9
  • [ 294-93-9 ]
  • [ 40891-99-4 ]
  • [ 64028-03-1 ]
  • [ 97571-68-1 ]
YieldReaction ConditionsOperation in experiment
35% With fluorine; sodium fluoride at -78 - 45℃;
  • 10
  • [ 294-93-9 ]
  • [ 2618-96-4 ]
  • 1,4,7,10-tetraoxacyclododecane-di(benzenesulfonyl)amine (1/2) [ No CAS ]
  • 11
  • [ 294-93-9 ]
  • [ 321660-75-7 ]
YieldReaction ConditionsOperation in experiment
74% With triethylamine pentahydrogen fluoride salt In acetonitrile at 20℃; Electrolysis;
  • 12
  • [ 294-93-9 ]
  • [ CAS Unavailable ]
  • [ CAS Unavailable ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
With lithium In (2)H8-toluene at 25℃; for 144h; Title compound not separated from byproducts;
  • 13
  • [ CAS Unavailable ]
  • [ 294-93-9 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
56% In tetrahydrofuran at 20℃;
  • 14
  • [ 294-93-9 ]
  • [ 80510-04-9 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
7% Stage #1: 1,2-bis(phosphino)benzene With n-butyllithium In tetrahydrofuran; hexane at -78 - 20℃; Stage #2: With arsenic trichloride In tetrahydrofuran; hexane at -78℃; Stage #3: (1,4,7,10-tetraoxacyclododecane) In tetrahydrofuran; hexane Further stages.;
  • 15
  • [ 294-93-9 ]
  • [ CAS Unavailable ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
65% In diethyl ether 0°C;
  • 16
  • [ 294-93-9 ]
  • [ CAS Unavailable ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
65% In diethyl ether 0°C,;
  • 17
  • [ 294-93-9 ]
  • [ 112039-97-1 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
65% In diethyl ether 0°C;
  • 18
  • [ 294-93-9 ]
  • [ CAS Unavailable ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
40% With THF In tetrahydrofuran addn. of 2 equiv. of 12-crown-4 to THF soln. of Li salt; crystn.;
  • 19
  • [ 294-93-9 ]
  • [ 5865-81-6 ]
  • [ 104712-92-7 ]
YieldReaction ConditionsOperation in experiment
59% With n-C4H9Li; C4H8O In diethyl ether; hexane (N2 or Ar), cooled soln. of SbHPh2 in Et2O treated dropwise with n-C4H9Li in hexane, allowed to warm to 0°C, 12-crown-4 added; precipitate dissolved in THF at room temp., filtered, slowly cooled to -20°C (crystn.);
  • 20
  • [ 294-93-9 ]
  • [ CAS Unavailable ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
65% With THF In diethyl ether recrystn. from THF/Et2O;
  • 21
  • [ 294-93-9 ]
  • [ CAS Unavailable ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
65% With THF In diethyl ether recrystn. from THF/Et2O;
  • 22
  • [ 294-93-9 ]
  • [ CAS Unavailable ]
  • [ 156025-43-3 ]
YieldReaction ConditionsOperation in experiment
68% In tetrahydrofuran addn. 12-crown-4 to soln. Cu-complex/THF, soln. stirred (2 h); addn. n-hexane (crystn.), elem. anal.;
  • 23
  • [ CAS Unavailable ]
  • [ 294-93-9 ]
  • [ 591-51-5 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
50% With THF In diethyl ether 1 equiv. of halide free PhLi was added to 1 equiv. of CuI in Et2O at 0°C, stirred for 15 min, filtered, ppt. suspended in Et2O, 1 equiv.of PhLi followed by 2 equiv. of crown ether were added; ppt. was redissolved in a min. vol. of warm THF, soln. cooled to -10°C, crystals collected;
  • 24
  • [ 294-93-9 ]
  • [ 112039-97-1 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
65% With THF In diethyl ether recrystn. from THF/Et2O;
  • 25
  • [ 294-93-9 ]
  • [ 128270-48-4 ]
  • [ 100-58-3 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
91% With Me3SiBr In tetrahydrofuran byproducts: MgBr2; N2-atmosphere; stirring soln. of Grignard reagent (slight excess) and o-silaborane at room temp. for 1 h, addn. of Me3SiBr, stirring for 15 min,addn. of soln. of crown-ether; filtration, crystn. of diffusion of hexane at 4°C, recrystn. (THF:Et2O); elem. anal.;
  • 26
  • [ 294-93-9 ]
  • [ 128270-48-4 ]
  • [ 676-58-4 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
89% With Me3SiCl In tetrahydrofuran byproducts: MgCl2; N2-atmosphere; stirring soln. of Grignard reagent (slight excess) and o-silaborane at room temp. for 1 h, addn. of Me3SiCl, stirring for 15 min,addn. of soln. of crown-ether; filtration, crystn. of diffusion of hexane at 4°C, recrystn. (THF:Et2O); elem. anal.;
  • 27
  • [ 294-93-9 ]
  • Lu(N(SiMe3)2)3 [ No CAS ]
  • [ 18027-10-6 ]
  • [Na((CH2CH2O)4)2](1+)*[Lu(N(Si(CH3)3)2)3(OSi(CH3)3)](1-)=[Na((CH2CH2O)4)2][Lu(N(Si(CH3)3)2)3(OSi(CH3)3)] [ No CAS ]
YieldReaction ConditionsOperation in experiment
100% In hexane dry atm.; molar ratio 1:1:2, stirring (room temp., 6 h); filtn., washing (n-hexane), drying (vac.); elem. anal.;
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