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Chemical Structure| 299949-24-9 Chemical Structure| 299949-24-9

Structure of 299949-24-9

Chemical Structure| 299949-24-9

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Product Details of [ 299949-24-9 ]

CAS No. :299949-24-9
Formula : C15H18N2O3
M.W : 274.32
SMILES Code : O=C(C1=C(C)NC(NC1C2=CC=C(C)C=C2)=O)OCC
MDL No. :MFCD00719779

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Application In Synthesis of [ 299949-24-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 299949-24-9 ]

[ 299949-24-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 299949-24-9 ]
  • [ 52693-87-5 ]
  • [ 17356-08-0 ]
  • [ 57-13-6 ]
  • [ 145091-87-8 ]
YieldReaction ConditionsOperation in experiment
58%; 55% With hydrazine hydrate; In neat (no solvent); for 6h;Reflux; General procedure: Amixture ofDHPMs a-h(0.01mol) and excess hydrazine hydrate (5 mL) was heatedunder reflux for 6 h. The reaction mixture was allowed tocool and poured on crushed ice.The obtained solid producta-d was filtered, crystallized from ethanol, and finallydried.The evaporation of the filtrate gave solid residue whichupon fractional crystallization from water gave the pyrazole and urea (a)/thiourea (b), respectively. 2.4.1. 3-Methyl-1H-pyrazol-5-ol (13). Yield: 42-55% (for a-h); m.p. 221-223 C (Lit. [49] m.p. 220-222 C); 1H-NMR(DMSO-6) δ (ppm): 2.47 (s, 3H, -CH3), 6.83 (s, 1H, Ar-H),10.07 (s, 1H, OH), 12.10 (s, 1H,NH).
 

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