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Chemical Structure| 15332-10-2 Chemical Structure| 15332-10-2

Structure of 3,3'-Difluorobenzaldazine
CAS No.: 15332-10-2

Chemical Structure| 15332-10-2

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3,3'-Difluorobenzaldazine (DFB) is a selective positive allosteric modulator of mGluR5 that enhances the effects of glutamate and other agonists, with an EC50 range of 2 to 5 µM, suitable for neurological research.

Synonyms: DFB

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Product Details of 3,3'-Difluorobenzaldazine

CAS No. :15332-10-2
Formula : C14H10F2N2
M.W : 244.24
SMILES Code : FC1=CC(/C=N/N=C/C2=CC=CC(F)=C2)=CC=C1
Synonyms :
DFB
MDL No. :MFCD03653615
InChI Key :YYMCVDNIIFNDJK-BEQMOXJMSA-N
Pubchem ID :6604893

Safety of 3,3'-Difluorobenzaldazine

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H318-H400
Precautionary Statements:P273-P280-P301+P312+P330-P305+P351+P338+P310
Class:9
UN#:3077
Packing Group:

Related Pathways of 3,3'-Difluorobenzaldazine

GPCR

Isoform Comparison

Biological Activity

Description
3,3'-Difluorobenzaldazine (DFB) acts as a selective positive allosteric modulator of mGluR5, enhancing the effect of mGlu5 agonists (Glutamate, Quisqualate, and 3,5-Dihydroxyphenylglycine) by 3- to 6-fold with EC50 values between 2 and 5 μM[1].

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