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Chemical Structure| 31575-75-4 Chemical Structure| 31575-75-4

Structure of 31575-75-4

Chemical Structure| 31575-75-4

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Product Details of [ 31575-75-4 ]

CAS No. :31575-75-4
Formula : C13H11BrO
M.W : 263.13
SMILES Code : BrC1=CC=CC=C1OCC2=CC=CC=C2
MDL No. :MFCD03427006
InChI Key :NBHAHMHUMMWFPJ-UHFFFAOYSA-N
Pubchem ID :561828

Safety of [ 31575-75-4 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 31575-75-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 31575-75-4 ]

[ 31575-75-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 28785-06-0 ]
  • [ 31575-75-4 ]
  • C23H24O2 [ No CAS ]
YieldReaction ConditionsOperation in experiment
General procedure: In a nitrogen stream, 2.6 M nBuLi in hexane (3.5 mL, 9.1 mmol) was added dropwise to a solution of 1-benzyloxy-2-bromobenzene (2.2 g, 8.3 mmol) in THF (83 mL) at -78 °C and the mixture was stirred at the same temperature for 30 min. To this solution, a solution of 4-cyclopropylbenzaldehyde (1.1 g, 6.9 mmol) in THF (280 mL) was added dropwise at -78 °C. The reaction mixture was stirred at the same temperature for 1 h. Water was added thereto and the mixture was extracted with AcOEt. The organic layer was washed with brine and dried with MgSO4, and then the solvent was removed under reduced pressure. The obtained residue was purified by silica gel column chromatography (AcOEt/hexane = 1:5) to obtain the title compound (1.7 g, 75percent)
 

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