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Chemical Structure| 3161-52-2 Chemical Structure| 3161-52-2

Structure of 3161-52-2

Chemical Structure| 3161-52-2

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Product Details of [ 3161-52-2 ]

CAS No. :3161-52-2
Formula : C11H16ClN
M.W : 197.70
SMILES Code : CN(CCCCl)CC1=CC=CC=C1
MDL No. :MFCD11977669

Safety of [ 3161-52-2 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H315-H318-H335
Precautionary Statements:P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P310-P330-P332+P313-P362-P403+P233-P405-P501

Application In Synthesis of [ 3161-52-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 3161-52-2 ]

[ 3161-52-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 3161-52-2 ]
  • [ 19932-85-5 ]
  • 3-[3-(N-benzyl-N-methylamino)propyl]-6-bromobenzoxazolin-2-one [ No CAS ]
YieldReaction ConditionsOperation in experiment
95% With potassium carbonate; In N,N-dimethyl-formamide; at 70℃; General procedure: One equivalent of appropriate heterocyclic derivative was dissolved in DMF. Three equivalents of potassium carbonate and 1.2 equivalent of the appropriate 3-chloropropan-1-amine derivative were added. The resulting mixture was heated at 70C until disappearance of the starting material. The reaction was monitored by TLC. After 24-96 h, the solvent was removed under reduced pressure, and water added to the residue. The crude product was extracted with dichloromethane. The combined organic fractions were washed with water and dried over magnesium sulphate. Purification by thick layer chromatography or column chromatography was performed.
 

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