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Chemical Structure| 318-31-0 Chemical Structure| 318-31-0

Structure of 318-31-0

Chemical Structure| 318-31-0

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Product Details of [ 318-31-0 ]

CAS No. :318-31-0
Formula : C13H8FNO
M.W : 213.21
SMILES Code : O=C1C2=C(C=CC=C2)NC3=CC=C(F)C=C13

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Application In Synthesis of [ 318-31-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 318-31-0 ]

[ 318-31-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 54-60-4 ]
  • [ 318-31-0 ]
YieldReaction ConditionsOperation in experiment
383 mg (59%) With trichlorophosphate; In water; 13.2 2-Fluoroacridone N-(4-Fluorophenyl)anthranilic acid (0.70 gm; 3 mmol) and phosphorous oxychloride (3 ml) were stirred together and heated to 115 C. for 3.5 hours, then allowed to cool. The reaction mixture was placed on ice and small pieces of ice added, a vigorous reaction occurred with the evolution of hydrogen chloride. When the reaction had subsided, water (15 ml) was added and the mixture was boiled for 2 hours. On cooling, a solid precipitated out. This was filtered off and washed with water until the filtrate was colourless. The precipitate was further washed with cold methanol then diethyl ether and dried under vacuum to give 383 mg (59%) of 2-fluoroacridone.
 

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