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Chemical Structure| 3233-32-7 Chemical Structure| 3233-32-7

Structure of 4-Hydroxyphenyl acetate
CAS No.: 3233-32-7

Chemical Structure| 3233-32-7

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4-Hydroxyphenyl acetate is a natural antioxidant that protects cells from necrosis caused by oxidative stress, upregulating NQO1 and HO-1 genes by stabilizing and inducing NRF2 nuclear translocation to inhibit ROS generation.

Synonyms: 4-HPA; 4-Acetoxyphenol

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Product Details of 4-Hydroxyphenyl acetate

CAS No. :3233-32-7
Formula : C8H8O3
M.W : 152.15
SMILES Code : CC(=O)OC1=CC=C(O)C=C1
Synonyms :
4-HPA; 4-Acetoxyphenol
MDL No. :MFCD00799234
InChI Key :HBMCQTHGYMTCOF-UHFFFAOYSA-N
Pubchem ID :96009

Safety of 4-Hydroxyphenyl acetate

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P280-P305+P351+P338

Isoform Comparison

Biological Activity

Description
4-Hydroxyphenyl acetate (4-HPA) functions as a natural antioxidant, offering protection against oxidative stress-induced necrosis in cells. It mitigates the rise in cellular reactive oxygen species (ROS) prompted by oxidative stress and promotes the expression of the NQO1 and HO-1 genes by facilitating the stabilization and nuclear translocation of the NRF2 transcription factor[1].

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

6.57mL

1.31mL

0.66mL

32.86mL

6.57mL

3.29mL

65.72mL

13.14mL

6.57mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

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