Home Cart 0 Sign in  

[ CAS No. 343778-59-6 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 343778-59-6
Chemical Structure| 343778-59-6
Structure of 343778-59-6 * Storage: {[proInfo.prStorage]}
Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Quality Control of [ 343778-59-6 ]

Related Doc. of [ 343778-59-6 ]

Alternatived Products of [ 343778-59-6 ]

Product Details of [ 343778-59-6 ]

CAS No. :343778-59-6 MDL No. :
Formula : C12H17ClN2 Boiling Point : -
Linear Structure Formula :- InChI Key :-
M.W : 224.73 Pubchem ID :-
Synonyms :

Safety of [ 343778-59-6 ]

Signal Word: Class:
Precautionary Statements: UN#:
Hazard Statements: Packing Group:

Application In Synthesis of [ 343778-59-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 343778-59-6 ]

[ 343778-59-6 ] Synthesis Path-Downstream   1~17

  • 1
  • [ 1722-12-9 ]
  • [ 343778-59-6 ]
  • [1-(3-Chloro-benzyl)-piperidin-4-yl]-pyrimidin-2-yl-amine [ No CAS ]
YieldReaction ConditionsOperation in experiment
42% With potassium carbonate In xylene for 24h; Heating;
  • 2
  • [ 68726-75-0 ]
  • [ 343778-59-6 ]
YieldReaction ConditionsOperation in experiment
60% With lithium aluminium tetrahydride In tetrahydrofuran; diethyl ether for 19h; Heating;
Stage #1: 1-(m-chlorobenzyl)-4-piperidone oxime With lithium aluminium tetrahydride In tetrahydrofuran for 2h; Heating / reflux; Stage #2: With sodium hydroxide; water In tetrahydrofuran 42.2.C.c Scheme C, step c: 4-Amino-1-(3-chlorobenzyl)piperidine; 4-Amino-1-(3-chlorobenzyl)piperidine is prepared from 1-(3-chlorobenzyl)-4-piperidone oxime essentially as described above in Example 38, Scheme C, step c.
  • 4
  • [ 380423-97-2 ]
  • [ 343778-59-6 ]
YieldReaction ConditionsOperation in experiment
With bis-[(trifluoroacetoxy)iodo]benzene In water; acetonitrile at 65℃;
Stage #1: 4-carboxamide-1-(3-chlorobenzyl)piperidine With phenylmethylene bis(2,2,2-trifluoroacetate) In water; acetonitrile at 65℃; Stage #2: With hydrogenchloride In water; acetonitrile at 0℃; Stage #3: With sodium carbonate In water 42.1.B.b Scheme B, step b: 4-Amino-1-(3-chlorobenzyl)piperidine; 4-Amino-1-(3-chlorobenzyl)piperidine is prepared from 4-carboxamide-1-(3-chlorobenzyl)piperidine essentially as described above in Example 38, Scheme B, step b.
  • 5
  • [ 343778-59-6 ]
  • 2-[trans-(4-aminocyclohexyl)amino]-6-[4-(1-(3-chlorobenzyl))piperidinylamino]-9-cyclopentylpurine [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: ethanol / Heating 2: 24 h / 150 °C
  • 6
  • [ 620-20-2 ]
  • [ 343778-59-6 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: Cs2CO3; KI / various solvent(s) / 5 h / 100 °C 2: PhI(CF3CO2)2 / acetonitrile; H2O / 65 °C
  • 7
  • [ 766-80-3 ]
  • [ 343778-59-6 ]
YieldReaction ConditionsOperation in experiment
16.a a a 4-Amino-1-(3-chlorobenzyl)-piperidine This compound was prepared using the procedure described in Example 8, Step C, using 3-chlorobenzylbromide in place of bromoethylbenzene.
Multi-step reaction with 3 steps 1: tetra-(n-butyl)ammonium iodide; potassium carbonate / acetonitrile / 24 h / Reflux 2: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 72.33 h / 0 - 20 °C / Inert atmosphere 3: hydrazine hydrate / methanol / 24 h / 20 °C
Multi-step reaction with 2 steps 1: triethylamine / ethanol 2: trifluoroacetic acid / dichloromethane / 4 h / 20 °C
  • 9
  • [ 5382-16-1 ]
  • [ 343778-59-6 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 3 steps 1: tetra-(n-butyl)ammonium iodide; potassium carbonate / acetonitrile / 24 h / Reflux 2: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 72.33 h / 0 - 20 °C / Inert atmosphere 3: hydrazine hydrate / methanol / 24 h / 20 °C
  • 10
  • 2-[1-(3-chloro)benzylpiperidin-4-yl]isoindoline-1,3-dione [ No CAS ]
  • [ 343778-59-6 ]
YieldReaction ConditionsOperation in experiment
With hydrazine hydrate In methanol at 20℃; for 24h;
  • 11
  • C13H9N3O3 [ No CAS ]
  • [ 343778-59-6 ]
  • 1H-indole-5-carboxylic acid [1-(3-chloro)benzylpiperidin-4-yl]-amide [ No CAS ]
YieldReaction ConditionsOperation in experiment
In tetrahydrofuran at 20℃; for 24h; Inert atmosphere;
  • 12
  • 1-(3-chloro)benzylpiperidin-4-ol [ No CAS ]
  • [ 343778-59-6 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 72.33 h / 0 - 20 °C / Inert atmosphere 2: hydrazine hydrate / methanol / 24 h / 20 °C
  • 13
  • [ 73874-95-0 ]
  • [ 343778-59-6 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: triethylamine / ethanol 2: trifluoroacetic acid / dichloromethane / 4 h / 20 °C
Multi-step reaction with 2 steps 1.1: acetic acid / dichloromethane / 1 h / 20 °C 1.2: 16 h / 20 °C 2.1: trifluoroacetic acid / dichloromethane / 16 h / 0 - 20 °C
  • 15
  • [ 343778-59-6 ]
  • [ 53188-07-1 ]
  • N-(1-(3-chlorobenzyl)piperidin-4-yl)-6-hydroxy-2,5,7,8-tetramethylchromane-2-carboxamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
36% With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 12h;
  • 16
  • [ 587-04-2 ]
  • [ 343778-59-6 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1.1: acetic acid / dichloromethane / 1 h / 20 °C 1.2: 16 h / 20 °C 2.1: trifluoroacetic acid / dichloromethane / 16 h / 0 - 20 °C
  • 17
  • [ 343778-59-6 ]
  • [ 329-01-1 ]
  • 1-(1-(3-chlorobenzyl)piperidin-4-yl)-3-(3-(trifluoromethyl)phenyl)urea [ No CAS ]
YieldReaction ConditionsOperation in experiment
With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 16h;
Same Skeleton Products
Historical Records