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Chemical Structure| 34593-47-0 Chemical Structure| 34593-47-0

Structure of 34593-47-0

Chemical Structure| 34593-47-0

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Product Details of [ 34593-47-0 ]

CAS No. :34593-47-0
Formula : C12H16O2
M.W : 192.25
SMILES Code : OCC1=CC=C(OCC=C(C)C)C=C1

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Application In Synthesis of [ 34593-47-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 34593-47-0 ]

[ 34593-47-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 28090-12-2 ]
  • [ 34593-47-0 ]
YieldReaction ConditionsOperation in experiment
With methanol; sodium tetrahydroborate; at 20℃;Reflux; General procedure: Excess K2CO3 and a small amount of KI as the catalyst were added to a solution of the vanillin or 4-hydroxy benzaldehy (20mmol) in dimethyl formamide (80mL). After stirring for 30min, cyclopropylmethyl bromide or 3-methyl-butenyl bromide (22mmol) was added, and the resulting mixture was stirred at 65C for 3-6h. The reaction was monitored by TLC analysis. After completion of the reaction, the solid was filtered, and the solution was concentrated in vacuo. The crude product was purified by chromatography on silica gel using petroleum ether/ethyl acetate (5:1, v:v) as original eluent to give substituted hydroxy aldehydes. Then the substituted hydroxy aldehydes were reduced by sodium borohydride to give corresponding alcohols, and subsequently the alcohols were used to esterification with TMCA to give compounds 29-32 using EDCI-DMAP as activation system.
 

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