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Chemical Structure| 348081-42-5 Chemical Structure| 348081-42-5

Structure of 348081-42-5

Chemical Structure| 348081-42-5

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Product Details of [ 348081-42-5 ]

CAS No. :348081-42-5
Formula : C11H17N3O4
M.W : 255.27
SMILES Code : O=C(O)[C@H](NC(OC(C)(C)C)=O)CN1N=CC=C1
MDL No. :MFCD03428500

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Application In Synthesis of [ 348081-42-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 348081-42-5 ]

[ 348081-42-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 288-13-1 ]
  • [ 98541-64-1 ]
  • [ 348081-42-5 ]
YieldReaction ConditionsOperation in experiment
In acetonitrile; at 50℃; Pyrazole (0.185 g, 2.7 mmol) was taken up in MeCN (9 ml) and added to N-Boc-D-serine [beta]-lactone (Vederas, Arnold, Kalantar, J.Am.Chem. Soc. 1985, 107, 7105) (0.5 g) in MeCN (12 ml) followed by stirring overnight at 50[deg.] C. Solvent was removed in vacuo to yield a crude oil (630 mg) that was taken up in methanol and transferred to a Bond Elut PSA column. The column was washed with methanol prior to elution with 4% TFA/THF which afforded the subtitle compound (280 mg).
 

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