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Chemical Structure| 352359-20-7 Chemical Structure| 352359-20-7

Structure of 352359-20-7

Chemical Structure| 352359-20-7

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Product Details of [ 352359-20-7 ]

CAS No. :352359-20-7
Formula : C14H18BNO4
M.W : 275.11
SMILES Code : OB(C(N1C(OC(C)(C)C)=O)=C(C)C2=C1C=CC=C2)O
MDL No. :MFCD18427586

Safety of [ 352359-20-7 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H312-H332
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P330-P363-P501

Application In Synthesis of [ 352359-20-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 352359-20-7 ]

[ 352359-20-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 22034-13-5 ]
  • [ 352359-20-7 ]
  • tert-butyl 2-(2,1,3-benzothiadiazol-4-yl)-3-methyl-1H-indole-1-carboxylate [ No CAS ]
YieldReaction ConditionsOperation in experiment
84% With tetrakis(triphenylphosphine) palladium(0); potassium carbonate; In 1,4-dioxane; water; at 95℃; for 4h; After reacting lithium diisopropylamide (LDA) with N-Boc-3-methylindole in tetrahydrofuran (THF) at -20 ° C.,Triisopropyl borate was added and reacted for 1.5 hours to obtain N-Boc-3-methylindole-2-boronic acid.As shown by the following formula (8), "Boc" represents a tert-butoxycarbonyl group.Next, without isolating the obtained boronic acid, in the presence of tetrakis (triphenylphosphine) palladium (20 molpercent),The reaction was allowed to proceed at 95 ° C. for 4 hours in a mixed solvent of <strong>[22034-13-5]4-bromo-2,1,3-benzothiadiazole</strong> and dioxane / potassium carbonate aqueous solution to obtain an indolylbenzothiadiazole derivative 1a in a yield of 84percent
 

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