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Chemical Structure| 3636-65-5 Chemical Structure| 3636-65-5

Structure of 3636-65-5

Chemical Structure| 3636-65-5

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Product Details of [ 3636-65-5 ]

CAS No. :3636-65-5
Formula : C10H11ClO4S
M.W : 262.71
SMILES Code : O=C(OCC)CS(=O)(C1=CC=C(Cl)C=C1)=O
MDL No. :MFCD00018662
Boiling Point : No data available

Safety of [ 3636-65-5 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Application In Synthesis of [ 3636-65-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 3636-65-5 ]

[ 3636-65-5 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 14752-66-0 ]
  • [ 141-97-9 ]
  • [ 3636-65-5 ]
YieldReaction ConditionsOperation in experiment
85% With ammonium iodide; In dimethyl sulfoxide; at 20℃; for 7h;Electrolysis; General procedure: In a typical experiment, 1,3-dicarbonyl compounds (1 mmol), sodium sulfinates (1.2 mmol), DMSO (8 mL) and NH4I (4 mmol) were added to the undivided cell. The electrosynthesis was carried out in the undivided cell fitted with a Ni sheet cathode (2 cmx2.5 cmx0.02 cm) and a graphite rod anode at a constantcurrent (50 mA) at room temperature under magnetic stirring for 2 h and then continuously stirring for 5 h. After the reaction was finished, the electrolyte solution was decolorized with Na2S2O3, and then washed with distilled water (50 mL) and extracted withethyl acetate (10 mLx3). The solvent was removed under reduced pressure, and the crude product was purified by column chromatography on silica gel using petroleum ether-ethyl acetate (5:1) as eluent.
  • 2
  • [ 623-73-4 ]
  • [ 14752-66-0 ]
  • [ 3636-65-5 ]
YieldReaction ConditionsOperation in experiment
65% With dipotassium peroxodisulfate; 1,10-Phenanthroline; silver nitrate; In water; acetonitrile; at 70℃; for 4h; Add AgNO3 (0.05 mmol, 8.5 mg), 1,10-phen (0.05 mmol, 9.0 mg), K2S2O8 (0.25 mmol, 67.6 mg), 1d (0.5 mmol, 91.1 mg), 2a (1.0 mmol, 114.1 mg), MeCN / H2O = 10: 1 (2.0 mL). Then, the system was heated and stirred at 70 C for 4 hours in the air. The reaction system was quenched with a saturated sodium sulfite solution, extracted three times with ethyl acetate, and the organic layers were combined and dried over anhydrous sodium sulfate. Then the solvent was removed and the silica gel was adsorbed, and then the product β-carbonylsulfone 3da was obtained by column chromatography with a yield of 65%. The main test data of the prepared products are as follows. It can be known from analysis that the actual synthetic products are consistent with the theoretical analysis.
 

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