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Chemical Structure| 364793-89-5 Chemical Structure| 364793-89-5

Structure of 364793-89-5

Chemical Structure| 364793-89-5

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Product Details of [ 364793-89-5 ]

CAS No. :364793-89-5
Formula : C12H14INO2
M.W : 331.15
SMILES Code : IC1=CC=C(CC(N2CCOCC2)=O)C=C1
MDL No. :MFCD32183690

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Application In Synthesis of [ 364793-89-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 364793-89-5 ]

[ 364793-89-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 110-91-8 ]
  • [ 1798-06-7 ]
  • [ 364793-89-5 ]
YieldReaction ConditionsOperation in experiment
62.1% With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In N,N-dimethyl-formamide; at 20℃; for 16h; 2-(4-Iodo-phenyl)-l-morpholin-4-yl-ethano Triethylamine (5.30 mL, 38.0 mmol), HOBt (3.96 g, 28.5 mmol) and EDC.HCl (5.47 g, 28.5 mmol) were added to a solution of (4-iodo-phenyl)-acetic acid (5.0 g, 19.0 mmol) in DMF (100 mL) and stirred. After 5 min morpholine (2.0 mL, 22.9 mmol) was added at RT. The reaction mixture was stirred at RT for 16 h. The reaction mixture was poured into ice-cold water (50 mL) and obtained solid was filtered, dried to get 3.92 g (Yield: 62.1 %) of the title compound as a white solid. 1H NMR (DMSO-dg, 400 MHz, TMS) δ: 7.66-7.64 (2H, d), 7.04-7.02 (2H, d), 3.68 (2H, s), 3.54-3.42 (8H, m).
 

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