Home Cart Sign in  
Chemical Structure| 36822-09-0 Chemical Structure| 36822-09-0

Structure of 36822-09-0

Chemical Structure| 36822-09-0

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 36822-09-0 ]

CAS No. :36822-09-0
Formula : C10H5ClN2S
M.W : 220.68
SMILES Code : ClC1=C2C(C3=CC=CC=C3S2)=NC=N1
MDL No. :MFCD01830285
InChI Key :GRJAFENSUSLYET-UHFFFAOYSA-N
Pubchem ID :821835

Safety of [ 36822-09-0 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 36822-09-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 36822-09-0 ]

[ 36822-09-0 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 36822-09-0 ]
  • [ 18628-07-4 ]
  • C34H20N4S [ No CAS ]
YieldReaction ConditionsOperation in experiment
90% With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; tris-(dibenzylideneacetone)dipalladium(0); sodium t-butanolate; In 5,5-dimethyl-1,3-cyclohexadiene; for 18h;Reflux; 4-Chlorobenzo[4,5]thieno[3,2-d]pyrimidine (1.992 g, 9.03 mmol) and 9H-3,9'-bicarbazole (2.000 g, 6.02 mmol), sodium 2-methylpropan-2-olate (1.156 g, 12.03 mmol), Pd2(dba)3 (250 mg) and dicyclohexyl(2',6'-dimethoxy-[1,1'-biphenyl]-2-yl)phosphine (SPhOS) (310 mg) were suspended in xylene (100 ml), degassed and heated to reflux for 18 hr. The reaction solution was cooled down, filtered through celite plug and evaporated. Column chromatography on silica gel column, eluted with hexane/DCM 1/1 (v/v), then hexane/EtOAc 4/1 (v/v), followed by crystallyzation from hexane/DCM provided yellow crystals (2.8 g, 90% yield).
  • 2
  • [ 36822-09-0 ]
  • [ 56525-79-2 ]
  • C34H21N3S [ No CAS ]
YieldReaction ConditionsOperation in experiment
1.4 g With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; tris-(dibenzylideneacetone)dipalladium(0); sodium t-butanolate; In m-xylene;Reflux; Inert atmosphere; 3,6-Diphenyl-9H-carbazole (3.0 g, 9.39 mmol), 4-chlorobenzo[4,5]thieno[3,2-d]pyrimidine (2.280 g, 10.33 mmol), sodium 2-methylpropan-2-olate (2.257 g, 23.48 mmol), Pd2dba3 (0.430 g, 0.470 mmol), and dicyclohexyl(2',6'-dimethoxy-[1,1'-biphenyl]-2-yl)phosphine (SPhos) (0.386 g, 0.939 mmol) were charged into a 250-mL round-bottom-flask (RBF), diluted in m-xylene (94 ml), degassed and heated to reflux overnight. Then the mixture was cooled down to room temperature and was diluted by DCM, filtered through a pad of Celite and washed with DCM. The solvent was evaporated and the crude solid was purified by column chromatography on silica, eluted with 30-50percent DCM in heptanes gradient mixture, then by 50/45/5 (v/v/v) DCM/heptanes/ethyl acetate mixture. After evaporation of the solvent, the yellow solid is triturated in methanol, then the solid was crystallized from heptanes/toluene mixture to provide 1.4 g of the pure Compound 1 (4-(3,6-diphenyl-9H-carbazol-9-yl) benzo [4,5] thieno [3,2-d]pyrimidine).
 

Historical Records

Technical Information

Categories

Related Functional Groups of
[ 36822-09-0 ]

Chlorides

Chemical Structure| 16269-66-2

A132700 [16269-66-2]

4-Chlorothieno[3,2-d]pyrimidine

Similarity: 0.93

Chemical Structure| 55115-80-5

A606907 [55115-80-5]

4-Chloropyrido[3',2':4,5]thieno[3,2-d]pyrimidine

Similarity: 0.88

Chemical Structure| 16234-14-3

A188460 [16234-14-3]

2,4-Dichlorothieno[3,2-d]pyrimidine

Similarity: 0.88

Chemical Structure| 319442-16-5

A586802 [319442-16-5]

4-Chloro-2-methylthieno[3,2-d]pyrimidine

Similarity: 0.86

Chemical Structure| 1823338-14-2

A372533 [1823338-14-2]

4,7-Dichlorothieno[3,2-d]pyrimidine

Similarity: 0.85

Related Parent Nucleus of
[ 36822-09-0 ]

Other Aromatic Heterocycles

Chemical Structure| 16269-66-2

A132700 [16269-66-2]

4-Chlorothieno[3,2-d]pyrimidine

Similarity: 0.93

Chemical Structure| 55115-80-5

A606907 [55115-80-5]

4-Chloropyrido[3',2':4,5]thieno[3,2-d]pyrimidine

Similarity: 0.88

Chemical Structure| 16234-14-3

A188460 [16234-14-3]

2,4-Dichlorothieno[3,2-d]pyrimidine

Similarity: 0.88

Chemical Structure| 319442-16-5

A586802 [319442-16-5]

4-Chloro-2-methylthieno[3,2-d]pyrimidine

Similarity: 0.86

Chemical Structure| 1823338-14-2

A372533 [1823338-14-2]

4,7-Dichlorothieno[3,2-d]pyrimidine

Similarity: 0.85