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Chemical Structure| 38158-65-5 Chemical Structure| 38158-65-5

Structure of 38158-65-5

Chemical Structure| 38158-65-5

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Product Details of [ 38158-65-5 ]

CAS No. :38158-65-5
Formula : C14H15N
M.W : 197.28
SMILES Code : CC1=CC=C(C=C1)N(C)C2=CC=CC=C2

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Application In Synthesis of [ 38158-65-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 38158-65-5 ]

[ 38158-65-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 121-69-7 ]
  • [ 262373-15-9 ]
  • [ 38158-65-5 ]
  • [ 92115-21-4 ]
YieldReaction ConditionsOperation in experiment
With potassium fluoride; 18-crown-6 ether; ammonium bicarbonate; In tetrahydrofuran; at 60℃; for 12h;Inert atmosphere; General procedure: f1e To a flame-dried screw-capped tube equipped with a magnetic stirN - bar were added 18-crown-6 (0.3 17 g, 1.2 mmol), KF (0.070 g, 1.2I .- 29 mmol) and NH4HCO3 (0.040 g, 0.50, mmol).Then the screw-capped tube was evacuated and backfilled with argon. Themixture was dissolved in THF (2.0 mL) under argon atmosphere and then to thestirring solution were added the N, N-dimethylaniline 1 (0.06 1 g, 65 ML, 0.50 mmol)and 2-(trimethylsilyl) phenyltrifluoro-methanesulfonate 2 (0.179 g, 146 pL, 0.60mmol) at room temperature (27C). Then the screw-capped tube kept in a preheatedoil bath at 60 C for 12 h. The reaction mixture cooled and the residue on column chromatography afforded N-methyl-N-phenylaniline 3 as a colourless oil (0.087 g, 95%),Rj(Pet. ether/DCM 90/10): 0.66;
 

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