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Chemical Structure| 40125-48-2 Chemical Structure| 40125-48-2

Structure of 40125-48-2

Chemical Structure| 40125-48-2

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Product Details of [ 40125-48-2 ]

CAS No. :40125-48-2
Formula : C8H4BrClO2
M.W : 247.47
SMILES Code : O=C1OC(Br)C2=C1C=C(Cl)C=C2

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Application In Synthesis of [ 40125-48-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 40125-48-2 ]

[ 40125-48-2 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 19641-29-3 ]
  • [ 40125-48-2 ]
YieldReaction ConditionsOperation in experiment
With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); In tetrachloromethane;Reflux; Irradiation; General procedure: Step 1 and 2: To isobenzofuran-1(3H)-one (7.7 mmol, 1 equiv) in 100 mL oftetracarbonchloride was added N-bromosuccinimide (9.24 mmol, 1.2 equiv.),azobisisobutyronitrile (0.77 mmol, 0.1 equiv.). The resulting mixture was refluxed underirradiation with 200 W lamp for 6 h. The solvent was evaporated and water (50 mL) wasadded and the resulting mixture refluxed for 2 h. The reaction mixture was then cooled toroom temperature and kept at -10 C overnight. The precipitate was filtered and dried invacuum to give the desired product.
  • 2
  • [ 19641-29-3 ]
  • 2,2'-azobisbutyronitrile [ No CAS ]
  • [ 40125-48-2 ]
YieldReaction ConditionsOperation in experiment
With N-Bromosuccinimide; In tetrachloromethane; b. 3-Bromo-6-Chloro-Phthalide 6-Chlorophthalide (7.66 gms; 0.0452 mole), N-bromosuccinimide (8.1 gms; 0.0452 mole) and azobisbutyronitrile (0.1 gm) were gently refluxed in dry carbon tetrachloride (150 ml.) for 11/2 hours. On cooling, the succinimide was filtered off and the solvent removed in vacuo to leave a yellow solid, which was used immediately. Yield 9.57 gms. 86.2%
 

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