Home Cart Sign in  
Chemical Structure| 4027-39-8 Chemical Structure| 4027-39-8

Structure of 4027-39-8

Chemical Structure| 4027-39-8

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 4027-39-8 ]

CAS No. :4027-39-8
Formula : C9H13NO3
M.W : 183.20
SMILES Code : O=C(C(CC1)=C(C)NC1=O)OCC

Safety of [ 4027-39-8 ]

Application In Synthesis of [ 4027-39-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 4027-39-8 ]

[ 4027-39-8 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 4027-39-8 ]
  • [ 3424-43-9 ]
YieldReaction ConditionsOperation in experiment
62% With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In 1,4-dioxane; for 5.0h;Heating / reflux; Ethyl 2-methyl-6-oxo-l,4,5,6-tetrahydropyridine-3-carboxylate (2g, 10.93mmol) and DDQ (5.21g, 22.95mmol) in 1,4-dioxaxne (110ml) were heated under reflux for 5h. The residue obtained after evaporation of solvent under reduced pressure was partitioned between DCM and water and washed with sat. sodium hydrogen carbonate solution. The aqueous layer was extracted with DCM twice. The organics were combined, washed with brine, dried and the solvent was evaporated to give a solid which was purified by chromatography eluting with MeOH:DCM (1 :99 to 4:96). Insoluble material in DCM and MeOH, prior to purification, was filtered off to give pure product. The product obtained after purification was dissolved in DCM and passed through a pre-equilibrated neutral alumina column, eluting with DCM, then 5% MeOH:DCM. Re-evaporation of solvent gave the title compound as a solid which was dried in vac oven overnight at 50C (1.23g, 62%). NMR (400MHz): 1.28 (t, 3H), 2.53 (s, 3H), 4.21 (q, 2H), 6.21 (d, IH), 7.82 (d, IH), 12.00 (s, IH); m/z 182. As an alternative to the above, the reaction mixture may be diluted with DCM and passed through a pre-equilibrated neutral alumina column, eluting with DCM, then MeOH. EPO <DP n="62"/>Chromatography on silica gel, then neutral alumina column eluting with DCM gave the product.
  • 2
  • [ 4027-39-8 ]
  • [ 546-67-8 ]
  • 2-acetoxymethyl-6-oxo-1,6-dihydro-pyridine-3-carboxylic acid ethyl ester [ No CAS ]
  • 2-acetoxymethyl-6-oxo-1,4,5,6-tetrahydro-pyridine-3-carboxylic acid ethyl ester [ No CAS ]
  • [ 3424-43-9 ]
 

Historical Records