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Chemical Structure| 41372-97-8 Chemical Structure| 41372-97-8

Structure of 41372-97-8

Chemical Structure| 41372-97-8

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Product Details of [ 41372-97-8 ]

CAS No. :41372-97-8
Formula : C13H10ClN3
M.W : 243.69
SMILES Code : ClC1=NC=CC2=C1C=NN2CC3=CC=CC=C3

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Application In Synthesis of [ 41372-97-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 41372-97-8 ]

[ 41372-97-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 871836-51-0 ]
  • [ 100-39-0 ]
  • [ 41372-97-8 ]
YieldReaction ConditionsOperation in experiment
3.1 g To a solution of <strong>[871836-51-0]4-chloro-1H-pyrazolo[4,3-c]pyridine</strong> (3.7 g) in THF (40 mL) was added NaH (1.93 g, 60% purity) at 0C. After stirring for 1 hour, benzyl bromide (3.15 mL) was added, and the mixture was stirred at 15C for 15 hours. The reaction mixture was quenched with water and extracted ethyl acetate. The organic layers were washed with brine, dried over Na2SO4, concentrated, and purified by silica gel chromatography (petroleum ether : ethyl acetate = 50 : 1 to 20 : 1) to give the target compound (3.1 g) as a solid. (2045) [00999] MS: (M+H+): 244.0
 

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