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Chemical Structure| 4505-48-0 Chemical Structure| 4505-48-0

Structure of 4505-48-0

Chemical Structure| 4505-48-0

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Product Details of [ 4505-48-0 ]

CAS No. :4505-48-0
Formula : C15H12
M.W : 192.26
SMILES Code : C1C(=CC2=CC=CC=C12)C1=CC=CC=C1
MDL No. :MFCD00239514

Safety of [ 4505-48-0 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P280-P305+P351+P338

Application In Synthesis of [ 4505-48-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 4505-48-0 ]

[ 4505-48-0 ] Synthesis Path-Downstream   1~3

  • 3
  • [ 591-50-4 ]
  • [ 10485-09-3 ]
  • [ 4505-48-0 ]
YieldReaction ConditionsOperation in experiment
76% With nickel(II) iodide; Bathocuproine; tetrabutylammomium bromide; zinc; In N,N-dimethyl acetamide; at 30℃; for 10h;Inert atmosphere; Glovebox; General procedure: To an oven-dried 10 mL reaction tube equipped with a magnetic stir bar was introduced in an argonfilledglove box. NiI2 (5 mol%, 7.8 mg), Bathocuproine (5 mol%, 9.0 mg), n-Bu4NBr (1.0 equiv., 161.2 mg) andzinc dust (1.5 equiv. 49 mg) were added. Then anhydrous DMA (4 mL) were added, and the mixture was stirredat which time aryl bromide (1 equiv. 0.5 mmol), alkenyl bromide (1 equiv. 0.5 mmol) were added to the resultingmixture in this order. The tube was sealed with a rubber stopper, stirred at room temperature for 10 h. After thereaction was complete, ethyl acetate (50 mL) added and the mixture was extracted with water (20 mL x 3). Thecombined organic layers were dried over Na2SO4 and concentrated under reduced pressure. The resulting crudeproduct was separated on a silica gel column with petroleum ether and ethyl acetate as eluent to afford the desired product.
 

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