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Chemical Structure| 4530-37-4 Chemical Structure| 4530-37-4

Structure of 4530-37-4

Chemical Structure| 4530-37-4

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Product Details of [ 4530-37-4 ]

CAS No. :4530-37-4
Formula : C16H22N2O5
M.W : 322.36
SMILES Code : O=C(O)[C@H](CC1=CC=CC=C1)NC(CNC(OC(C)(C)C)=O)=O

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Application In Synthesis of [ 4530-37-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 4530-37-4 ]

[ 4530-37-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 24424-99-5 ]
  • [ 3321-03-7 ]
  • [ 4530-37-4 ]
YieldReaction ConditionsOperation in experiment
81% With guanidine hydrochloride; In ethanol; at 35 - 40℃; for 9.5h; General procedure: Amino acid or peptide (1 mmol) was added with stirring to a solution of guanidine hydrochloride (15 mol%) and di-tert-butyl dicarbonate (2.5-3 mmol) in EtOH (1 mL), at 35-40C. The reaction mixture was continued to stir until a clear solution was obtained. EtOH was evaporated under vacuum and the residue was successively washed with water (2 mL) and hexane or petroleum ether (2 mL) to afford almost pure N-Boc amino acids or N-Boc peptides. If necessary, the crude products could be recrystallized for further purification.
 

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