Purity | Size | Price | VIP Price | USA Stock *0-1 Day | Global Stock *5-7 Days | Quantity | |||||
{[ item.p_purity ]} | {[ item.pr_size ]} |
{[ getRatePrice(item.pr_usd, 1,1) ]} {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate) ]} |
{[ getRatePrice(item.pr_usd, 1,1) ]} | Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate) ]} {[ getRatePrice(item.pr_usd,1,item.mem_rate) ]} | {[ item.pr_usastock ]} | Inquiry - | {[ item.pr_chinastock ]} | Inquiry - |
* Storage: {[proInfo.prStorage]}
CAS No. : | 4737-50-2 | MDL No. : | MFCD01074651 |
Formula : | C5H13BO2 | Boiling Point : | - |
Linear Structure Formula : | - | InChI Key : | ABWPXVJNCQKYDR-UHFFFAOYSA-N |
M.W : | 115.97 | Pubchem ID : | 352103 |
Synonyms : |
|
Signal Word: | Warning | Class: | N/A |
Precautionary Statements: | P261-P305+P351+P338 | UN#: | N/A |
Hazard Statements: | H315-H319-H335 | Packing Group: | N/A |
GHS Pictogram: |
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
With sodium azide; copper diacetate; In water; acetonitrile; at 20℃; | General procedure: To the solution of particular phenylboronic acid (1eq) in acetonitrile: water 1:1 was added. Cu(OAc)2 (10mol%) and NaN3 (1.5 eq) and allowed to react at room temperature on magnetic stirrer. Upon completion, the reaction mixture was extracted with ethylacetate and water. The organic layer was concentrated on rota evaporated to furnish the corresponding azide in almost 98% yield and of sufficient purity to be used in the subsequent reactions (Scheme 2). |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
58% | With copper diacetate; potassium carbonate; In acetonitrile; at 60℃; for 10h;Schlenk technique; | General procedure: A 25 mL dried Schlenk tube was charged with boronic acid 1 (0.5 mmol), amine 2 (2.5 mmol), CS2 (1.0 mmol), Cu(OAc)2 (1.0 mmol), K2CO3 (1.5 mmol) and MeCN (4 mL) at room temperature. The reaction mixture was stirred at 60 C for 10 h under air. After the reaction was completed, the mixture was cooled to room temperature and filtered through a plug of celite. The filtrate was then concentrated in vacuo to afford the crude product, which was then subjected to chromatography on silica gel with hexanes/EtOAc (20:1) to give the desired product 3. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
85% | With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate tribasic trihydrate; palladium diacetate; In toluene; at 110℃; for 24h;Inert atmosphere; | 3.0 g (8.4 mmol) of acetic acid 3-(4-bromophenyl)-coumarin-7-yl ester, 1.0 g (8.8 mmol) of <strong>[4737-50-2]n-<strong>[4737-50-2]pentylboronic acid</strong></strong> and 3.7 g (17.5 mmol) of tn-potassium phosphatetrihydrate are dissolved in 80 ml of toluene and degassed. 171 rng (0.4 mmol) of2-dicyclohexylphoshino-2?,6?-dimethoxy-1,1?-biphenyl and 47 mg (0.2 mmol) ofpalladium(ll) acetate are added. The reaction mixture is subsequently stirred at110 C for 24 h under a protective-gas atmosphere. The cooled solution is dilutedwith ethyl acetate and washed with water, dried and evaporated. The product ispurified by column chromatography on silica gel (heptane/ethyl acetate). Yield:2.5 g (7.1 mmol), 85% of theory. |
85% | With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate tribasic trihydrate; palladium diacetate; In toluene; at 110℃; for 24h;Inert atmosphere; | 3.0 g (8.4 mmol) of acetic acid 3-(4-bromophenyl)-coumarin-7-yl ester, (0495) 1 .0 g (8.8 mmol) of <strong>[4737-50-2]n-<strong>[4737-50-2]pentylboronic acid</strong></strong> and 3.7 g (17.5 mmol) of tri- potassium phosphate trihydrate are dissolved in 80 ml of toluene and degassed. 171 mg (0.4 mmol) of 2-dicyclohexylphoshino-2',6'-dimethoxy- (0496) 1 .1 '-biphenyl [S-Phos] and 47 mg (0.2 mmol) of palladium(ll) acetate are added. The reaction mixture is subsequently stirred at 1 10 C for 24 h under a protective-gas atmosphere. The cooled solution is diluted with ethyl acetate and washed with water, dried and evaporated. The product is purified by column chromatography on silica gel (heptane/ethyl acetate). Yield: 2.5 g (7.1 mmol), 85% of theory. |
85% | With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate tribasic trihydrate; palladium diacetate; In toluene; at 110℃; for 24h; | 3.0 g (8.4 mmol) of acetic acid 3-(4-bromophenyl)-coumarin-7-yl ester,.0 g (8.8 mmol) of <strong>[4737-50-2]n-<strong>[4737-50-2]pentylboronic acid</strong></strong> and 3.7 g (17.5 mmol) of tn-potassium phosphate trihydrate are dissolved in 80 ml of toluene anddegassed. 171 mg (0.4 mmol) of 2-dicyclohexylphoshino-2?,6?-dimethoxy-1,1 ?-biphenyl [S-Phos] and 47 mg (0.2 mmol) of palladium(ll) acetate areadded. The reaction mixture is subsequently stirred at 110 00 for 24 h under a protective-gas atmosphere. The cooled solution is diluted with ethyl acetate and washed with water, dried and evaporated. The product is purified by column chromatography on silica gel (heptane/ethyl acetate). Yield: 2.5 g (7.1 mmol), 85% of theory.Under the basic conditions, deprotection of the acetate group to the corresponding phenol could be observed during several Suzuki coupling reactions. To complete the deprotection step, the crude organic phase after workup is refluxed with a 1:2 mixture sulfuric acid (-2O%):ethanol untilcompletion. Then column chromatography of the obtained residue, as described above, is done.IH NMR (500 MHz, DMSO-d6) 68.23(s, 1H), 7.81 (d, 1H, J = 8.4 Hz), 7.64 (d, 2H, J = 8.2 Hz), 7.34-7.25 (m, 3H), 7.18 (dd, 1H, J = 8.4 Hz, J = 2.2 Hz),7.20 (dd, 1H, J = 8.4 Hz, J = 2.1 Hz), 2.62 (t, 2H, J = 7.6 Hz), 2.32 (5, 3H),1 .64-1 .58 (m, 2H), 1.37-1 .24 (m, 4H), 0.87 (t, 3H, J = 7.0 Hz). |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
General procedure: A mixture of t-butyl starting material (1.00 mmol), Pd(PPh3)4(0.10 mmol), and 2 M Na2CO3 (7.30 mmol) in toluene was refluxed for 30 min. After 30 min, to the reaction mixture was added boronicacid (2.00 mmol) in 1,4-dioxane. The reaction mixture was refluxed for 14 h. The reaction mixture was cooled to ambient temperature and extracted with EtOAc (10 mL). The aqueous phase was saturated with aq NaCl and extracted again with EtOAc(15 mL). The combined organic extracts were washed with 1 NHCl (5 mL) and brine (5 mL), dried over MgSO4, filtered, and concentrated in vacuo. The residue was purified by flash column chromatography on silica gel using EtOAc/hexanes (1:30) as eluant. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
95% | With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium phosphate; In toluene; at 110℃; for 16h;Inert atmosphere; Enzymatic reaction; | ?Suzuki route?: From compound 6, Table 2, entry 1. 100 mg of 1-bromo-3,5-dimethoxybenzene (0.46 mmol, 1 eq) was dissolved in 5 mL of toluene, and to this mixture was added 293 mg of potassium phosphate (1.38 mmol, 3 eq), 80 mg of <strong>[4737-50-2]pentylboronic acid</strong> (0.69 mmol, 1.5 eq), and 17 mg of [1,1'-bis(diphenylphosphino)ferrocene]-dichloropalladium (0.23 mmol, 0.05 eq). Solvent was degassed by deep-freezing method. The reaction mixture was stirred under argon at 110 C overnight. The mixture was filtered through a pack of celite and silica gel using ethyl acetate as eluent and then concentrated in vacuo using rotary evaporator to afford yellow oil. The crude product was dry loaded onto silica gel and purified by column chromatography (19:1 petrol ether:ethyl acetate) to afford 91 mg (95%) of product as a transparent colorless oil with identical analytical data obtainedby ?Sonogahira route?. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
84% | With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate monohydrate; palladium diacetate; In toluene; at 90℃; | General procedure: 2-(4-Bromo-phenyl)-6-methoxy-benzo[b]thiophene (480 mg, 1 .51 mmol), <strong>[4737-50-2]pentylboronic acid</strong> (209 mg, 1 .80 mmol) and tripotassium phosphate monohydrate (1 .45 g, 6.31 mmol) are dissolved in toluene (15 ml, 150 mmol). Then 2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl [SPhos] (124 mg, 0.301 mmol) and palladium(ll) acetate (8.4 mg, 0.040 mmol) are added and the reaction reaction mixture is heated to 90 C upon completion of the reaction. The cooled reaction mixture is diluted with ethyl acetate and HCI solution (2 M). The solution is transferred to a separatory funnel. The organic phase is extracted with HCI solution (2 M) and water and brine. The organic phase is dried over MgSO4, filtered and concentrated under reduced pressure. The residue is purified by silica gel column chromatography (heptane/ethyl acetate [5/1 ]) to yield 6-methoxy-2-(4- pentylphenyl)benzo[b]thiophene (390 mg, 1 .26 mmol, 84 % of theory).1 H NMR (500 MHz, CDCI3) delta 7.63 (d, 1 H, J = 8.7 Hz), 7.59 (d, 2H, J =8.2 Hz), 7.41 (s, 1 H), 7.30 (d, 1 H, J = 2.4 Hz), 7.25 (d, 2H, J = 8.1 Hz), 6.98 (dd, 1 H, J = 8.7 Hz, 2.4 Hz), 3.89 (s, 3H), 2.61 - 2.58 (m, 2H), 1 .56 (p, 2H, J = 7.5 Hz), 1 .30 - 1 .22 (m, 4H), 0.83 (t 3H, J = 6.9 Hz, 3H). |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
96% | With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate monohydrate; palladium diacetate; In toluene; at 120℃; for 24h; | 2-(4-Bromo-phenyl)-6-nnethoxy-benzofuran (550 mg; 1 ,81 mmol), <strong>[4737-50-2]pentylboronic acid</strong> (463 mg; 3,99 mmol) and tripotassium phosphate monohydrate (1 ,75 g; 7,62 mmol) are dissolved in toluene (19,2 ml; 181 mmol). Then 2-dicyclohexylphosphino-2',6'-dimethoxybiphenyl [SPhos] (149 mg; 359 muiotatauiotaomicronIota) and palladium(ll) acetate (40,7 mg; 180 muiotatauiotaomicronIota) are added and the reaction mixture is heated to 120 C for 1 d. The cooled reaction mixture is diluted with ethyl acetate and HCI solution (2 M). The solution is transferred to a separatory funnel. The organic phase is extracted with HCI solution (2 M) and water and brine. The organic phase is dried over MgS04, filtered and concentrated under reduced pressure. The residue is purified by silica gel column chromatography (heptane/ethyl acetate, 5/1 ) to yield 6-Methoxy-2-(4-pentyl-phenyl)-benzofuran (512 mg; 1 ,7 mmol; 96% of theory). (0472) 1 H NMR (500 MHz, Chloroform-d) delta 7.65 (d, J = 8.2 Hz, 2H), 7.35 (d, J = 8.5 Hz, 1 H), 7.17 (d, J = 8.1 Hz, 2H), 6.99 (d, J = 2.1 Hz, 1 H), 6.82 (s, 1 H), 6.79 (dd, J = 8.5, 2.3 Hz, 1 H), 3.80 (s, 3H), 2.59 - 2.54 (m, 2H), 1 .58 (p, J = 7.5 Hz, 2H), 1 .32 - 1 .24 (m, 4H), 0.83 (t, J = 6.9 Hz, 3H). |
96% | With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate monohydrate; palladium diacetate; In toluene; at 120℃; for 24h;Inert atmosphere; | 2-(4-Bromo-phenyl)-6-methoxy-benzofuran (550 mg; 1,81 mmol), <strong>[4737-50-2]pentylboronic acid</strong> (463 mg; 3,99 mmol) and tripotassium phosphate monohydrate (1,75 g; 7,62 mmol) are dissolved in toluene (19,2 ml; 181 mmol). Then 2-dicyclohexylphosphino-2',6'-dimethoxybiphenyl [SPhos] (149 mg; 359 muiotatauiotaomicronIota) and palladium(ll) acetate (40,7 mg; 180 muiotatauiotaomicronIota) are added and the reaction mixture is heated to 120 C for 1 d. The cooled reaction mixture is diluted with ethyl acetate and HCI solution (2 M). The solution is transferred to a separatory funnel. The organic phase is extracted with HCI solution (2 M) and water and brine. The organic phase is dried over MgSO4, filtered and concentrated under reduced pressure. The residue is purified by silica gel column chromatography (heptane/ethyl acetate, 5/1) to yield 6-Methoxy-2-(4-pentyl-phenyl)-benzofuran (512 mg; 1,7 mmol; 96% of theory). 1H NMR (500 MHz, Chloroform-d) delta 7.65 (d, J = 8.2 Hz, 2H), 7.35 (d, J = 8.5 Hz, 1H), 7.17 (d, J = 8.1Hz, 2H), 6.99 (d, J = 2.1Hz, 1H), 6.82 (s, 1H), 6.79 (dd, J = 8.5, 2.3 Hz, 1H), 3.80 (s, 3H), 2.59 - 2.54 (m, 2H), 1.58 (p, J = 7.5 Hz, 2H), 1.32 - 1.24 (m, 4H), 0.83 (t, J = 6.9 Hz, 3H). |
66% | With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate monohydrate; palladium diacetate; In toluene; at 120℃; for 24h; | General procedure: 2-(4-Bromo-phenyl)-6-methoxy-benzofuran (550 mg, 1 .81 mmol), <strong>[4737-50-2]pentylboronic acid</strong> (463 mg, 3.99 mmol) and tripotassium phosphate monohydrate (1 .75 g, 7.62 mmol) are dissolved in toluene (19.2 ml, 181 mmol). Then 2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl [SPhos] (149 mg, 359 muetaetaomicronIota) and palladium(ll) acetate (40.7 mg, 180 muetaetaomicronIota) are added and the reaction reaction mixture is heated to 120 C for 1 d. The cooled reaction mixture is diluted with ethyl acetate and HCI solution (2 M). The solution is transferred to a separatory funnel. The organic phase is extracted with HCI solution (2 M) and water and brine. The organic phase is dried over MgS04, filtered and concentrated under reduced pressure. The residue is purified by silica gel column chromatography (heptane/ethyl acetate [5/1 ]) to yield 6-Methoxy-2-(4-pentyl-phenyl)-benzofuran (350 mg, 1 .2 mmol, 66% of theory).1 H NMR (500 MHz, Chloroform-d) delta 7.65 (d, J = 8.2 Hz, 2H), 7.35 (d, J = 8.5 Hz, 1 H), 7.17 (d, J = 8.1 Hz, 2H), 6.99 (d, J = 2.1 Hz, 1 H), 6.82 (s, 1 H), 6.79 (dd, J = 8.5 Hz, 2.3 Hz, 1 H), 3.80 (s, 3H), 2.59 - 2.54 (m, 2H), 1 .58 (p, J = 7.5 Hz, 2H), 1 .32 - 1 .24 (m, 4H), 0.83 (t, J = 6.9 Hz, 3H). |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
90% | General procedure: 3.0 g (8.4 mmol) of acetic acid 3-(4-bromophenyl)-coumarin-7-yl ester,.0 g (8.8 mmol) of <strong>[4737-50-2]n-<strong>[4737-50-2]pentylboronic acid</strong></strong> and 3.7 g (17.5 mmol) of tn-potassium phosphate trihydrate are dissolved in 80 ml of toluene anddegassed. 171 mg (0.4 mmol) of 2-dicyclohexylphoshino-2?,6?-dimethoxy-1,1 ?-biphenyl [S-Phos] and 47 mg (0.2 mmol) of palladium(ll) acetate areadded. The reaction mixture is subsequently stirred at 110 00 for 24 h under a protective-gas atmosphere. The cooled solution is diluted with ethyl acetate and washed with water, dried and evaporated. The product is purified by column chromatography on silica gel (heptane/ethyl acetate). Yield: 2.5 g (7.1 mmol), 85% of theory.Under the basic conditions, deprotection of the acetate group to the corresponding phenol could be observed during several Suzuki coupling reactions. To complete the deprotection step, the crude organic phase after workup is refluxed with a 1:2 mixture sulfuric acid (-2O%):ethanol untilcompletion. Then column chromatography of the obtained residue, as described above, is done.IH NMR (500 MHz, DMSO-d6) 68.23(s, 1H), 7.81 (d, 1H, J = 8.4 Hz), 7.64 (d, 2H, J = 8.2 Hz), 7.34-7.25 (m, 3H), 7.18 (dd, 1H, J = 8.4 Hz, J = 2.2 Hz),7.20 (dd, 1H, J = 8.4 Hz, J = 2.1 Hz), 2.62 (t, 2H, J = 7.6 Hz), 2.32 (5, 3H),1 .64-1 .58 (m, 2H), 1.37-1 .24 (m, 4H), 0.87 (t, 3H, J = 7.0 Hz). |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
95% | General procedure: 3.0 g (8.4 mmol) of acetic acid 3-(4-bromophenyl)-coumarin-7-yl ester,.0 g (8.8 mmol) of <strong>[4737-50-2]n-<strong>[4737-50-2]pentylboronic acid</strong></strong> and 3.7 g (17.5 mmol) of tn-potassium phosphate trihydrate are dissolved in 80 ml of toluene anddegassed. 171 mg (0.4 mmol) of 2-dicyclohexylphoshino-2?,6?-dimethoxy-1,1 ?-biphenyl [S-Phos] and 47 mg (0.2 mmol) of palladium(ll) acetate areadded. The reaction mixture is subsequently stirred at 110 00 for 24 h under a protective-gas atmosphere. The cooled solution is diluted with ethyl acetate and washed with water, dried and evaporated. The product is purified by column chromatography on silica gel (heptane/ethyl acetate). Yield: 2.5 g (7.1 mmol), 85% of theory.Under the basic conditions, deprotection of the acetate group to the corresponding phenol could be observed during several Suzuki coupling reactions. To complete the deprotection step, the crude organic phase after workup is refluxed with a 1:2 mixture sulfuric acid (-2O%):ethanol untilcompletion. Then column chromatography of the obtained residue, as described above, is done.IH NMR (500 MHz, DMSO-d6) 68.23(s, 1H), 7.81 (d, 1H, J = 8.4 Hz), 7.64 (d, 2H, J = 8.2 Hz), 7.34-7.25 (m, 3H), 7.18 (dd, 1H, J = 8.4 Hz, J = 2.2 Hz),7.20 (dd, 1H, J = 8.4 Hz, J = 2.1 Hz), 2.62 (t, 2H, J = 7.6 Hz), 2.32 (5, 3H),1 .64-1 .58 (m, 2H), 1.37-1 .24 (m, 4H), 0.87 (t, 3H, J = 7.0 Hz). |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
84% | General procedure: 3.0 g (8.4 mmol) of acetic acid 3-(4-bromophenyl)-coumarin-7-yl ester,.0 g (8.8 mmol) of <strong>[4737-50-2]n-<strong>[4737-50-2]pentylboronic acid</strong></strong> and 3.7 g (17.5 mmol) of tn-potassium phosphate trihydrate are dissolved in 80 ml of toluene anddegassed. 171 mg (0.4 mmol) of 2-dicyclohexylphoshino-2?,6?-dimethoxy-1,1 ?-biphenyl [S-Phos] and 47 mg (0.2 mmol) of palladium(ll) acetate areadded. The reaction mixture is subsequently stirred at 110 00 for 24 h under a protective-gas atmosphere. The cooled solution is diluted with ethyl acetate and washed with water, dried and evaporated. The product is purified by column chromatography on silica gel (heptane/ethyl acetate). Yield: 2.5 g (7.1 mmol), 85% of theory.Under the basic conditions, deprotection of the acetate group to the corresponding phenol could be observed during several Suzuki coupling reactions. To complete the deprotection step, the crude organic phase after workup is refluxed with a 1:2 mixture sulfuric acid (-2O%):ethanol untilcompletion. Then column chromatography of the obtained residue, as described above, is done.IH NMR (500 MHz, DMSO-d6) 68.23(s, 1H), 7.81 (d, 1H, J = 8.4 Hz), 7.64 (d, 2H, J = 8.2 Hz), 7.34-7.25 (m, 3H), 7.18 (dd, 1H, J = 8.4 Hz, J = 2.2 Hz),7.20 (dd, 1H, J = 8.4 Hz, J = 2.1 Hz), 2.62 (t, 2H, J = 7.6 Hz), 2.32 (5, 3H),1 .64-1 .58 (m, 2H), 1.37-1 .24 (m, 4H), 0.87 (t, 3H, J = 7.0 Hz). |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
72% | With 1,4-diaza-bicyclo[2.2.2]octane; [4,4′-bis(1,1-dimethylethyl)-2,2′-bipyridine-N1,N1′]bis{3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-κN]phenyl-κC}iridium(III) hexafluorophosphate; caesium carbonate In dichloromethane at 20℃; Inert atmosphere; Irradiation; | General Procedure for amplification experiment General procedure: Under the protection of nitrogen, [Ir(dFCF3ppy)2(dtbbpy)]PF6 (0.025 mmol, 0.5mol%), 1a (5 mmol), 2a (10 mmol), DABCO (0.2 equiv), Cs2CO3 (2 equiv) and anhydrous DCM (50 ml) were added into a 100 ml three port flask. The reaction mixture was placed at a distance of about 5 cm from 45 w CFL, stirred at room temperature, and the reaction was tracked by TLC. After the reaction, H2O (100 ml) was added and the water layer was extracted with DCM (3 × 50 ml). The organic phase was combined, dried with anhydrous sodium sulfate, filtered, and the solvent was removed by rotary evaporator. The product 3a (1.03 g) was obtained by column chromatography (PE). |
Tags: 4737-50-2 synthesis path| 4737-50-2 SDS| 4737-50-2 COA| 4737-50-2 purity| 4737-50-2 application| 4737-50-2 NMR| 4737-50-2 COA| 4737-50-2 structure
Precautionary Statements-General | |
Code | Phrase |
P101 | If medical advice is needed,have product container or label at hand. |
P102 | Keep out of reach of children. |
P103 | Read label before use |
Prevention | |
Code | Phrase |
P201 | Obtain special instructions before use. |
P202 | Do not handle until all safety precautions have been read and understood. |
P210 | Keep away from heat/sparks/open flames/hot surfaces. - No smoking. |
P211 | Do not spray on an open flame or other ignition source. |
P220 | Keep/Store away from clothing/combustible materials. |
P221 | Take any precaution to avoid mixing with combustibles |
P222 | Do not allow contact with air. |
P223 | Keep away from any possible contact with water, because of violent reaction and possible flash fire. |
P230 | Keep wetted |
P231 | Handle under inert gas. |
P232 | Protect from moisture. |
P233 | Keep container tightly closed. |
P234 | Keep only in original container. |
P235 | Keep cool |
P240 | Ground/bond container and receiving equipment. |
P241 | Use explosion-proof electrical/ventilating/lighting/equipment. |
P242 | Use only non-sparking tools. |
P243 | Take precautionary measures against static discharge. |
P244 | Keep reduction valves free from grease and oil. |
P250 | Do not subject to grinding/shock/friction. |
P251 | Pressurized container: Do not pierce or burn, even after use. |
P260 | Do not breathe dust/fume/gas/mist/vapours/spray. |
P261 | Avoid breathing dust/fume/gas/mist/vapours/spray. |
P262 | Do not get in eyes, on skin, or on clothing. |
P263 | Avoid contact during pregnancy/while nursing. |
P264 | Wash hands thoroughly after handling. |
P265 | Wash skin thouroughly after handling. |
P270 | Do not eat, drink or smoke when using this product. |
P271 | Use only outdoors or in a well-ventilated area. |
P272 | Contaminated work clothing should not be allowed out of the workplace. |
P273 | Avoid release to the environment. |
P280 | Wear protective gloves/protective clothing/eye protection/face protection. |
P281 | Use personal protective equipment as required. |
P282 | Wear cold insulating gloves/face shield/eye protection. |
P283 | Wear fire/flame resistant/retardant clothing. |
P284 | Wear respiratory protection. |
P285 | In case of inadequate ventilation wear respiratory protection. |
P231 + P232 | Handle under inert gas. Protect from moisture. |
P235 + P410 | Keep cool. Protect from sunlight. |
Response | |
Code | Phrase |
P301 | IF SWALLOWED: |
P304 | IF INHALED: |
P305 | IF IN EYES: |
P306 | IF ON CLOTHING: |
P307 | IF exposed: |
P308 | IF exposed or concerned: |
P309 | IF exposed or if you feel unwell: |
P310 | Immediately call a POISON CENTER or doctor/physician. |
P311 | Call a POISON CENTER or doctor/physician. |
P312 | Call a POISON CENTER or doctor/physician if you feel unwell. |
P313 | Get medical advice/attention. |
P314 | Get medical advice/attention if you feel unwell. |
P315 | Get immediate medical advice/attention. |
P320 | |
P302 + P352 | IF ON SKIN: wash with plenty of soap and water. |
P321 | |
P322 | |
P330 | Rinse mouth. |
P331 | Do NOT induce vomiting. |
P332 | IF SKIN irritation occurs: |
P333 | If skin irritation or rash occurs: |
P334 | Immerse in cool water/wrap n wet bandages. |
P335 | Brush off loose particles from skin. |
P336 | Thaw frosted parts with lukewarm water. Do not rub affected area. |
P337 | If eye irritation persists: |
P338 | Remove contact lenses, if present and easy to do. Continue rinsing. |
P340 | Remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P341 | If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P342 | If experiencing respiratory symptoms: |
P350 | Gently wash with plenty of soap and water. |
P351 | Rinse cautiously with water for several minutes. |
P352 | Wash with plenty of soap and water. |
P353 | Rinse skin with water/shower. |
P360 | Rinse immediately contaminated clothing and skin with plenty of water before removing clothes. |
P361 | Remove/Take off immediately all contaminated clothing. |
P362 | Take off contaminated clothing and wash before reuse. |
P363 | Wash contaminated clothing before reuse. |
P370 | In case of fire: |
P371 | In case of major fire and large quantities: |
P372 | Explosion risk in case of fire. |
P373 | DO NOT fight fire when fire reaches explosives. |
P374 | Fight fire with normal precautions from a reasonable distance. |
P376 | Stop leak if safe to do so. Oxidising gases (section 2.4) 1 |
P377 | Leaking gas fire: Do not extinguish, unless leak can be stopped safely. |
P378 | |
P380 | Evacuate area. |
P381 | Eliminate all ignition sources if safe to do so. |
P390 | Absorb spillage to prevent material damage. |
P391 | Collect spillage. Hazardous to the aquatic environment |
P301 + P310 | IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
P301 + P312 | IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. |
P301 + P330 + P331 | IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. |
P302 + P334 | IF ON SKIN: Immerse in cool water/wrap in wet bandages. |
P302 + P350 | IF ON SKIN: Gently wash with plenty of soap and water. |
P303 + P361 + P353 | IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. |
P304 + P312 | IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell. |
P304 + P340 | IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. |
P304 + P341 | IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P305 + P351 + P338 | IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
P306 + P360 | IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes. |
P307 + P311 | IF exposed: call a POISON CENTER or doctor/physician. |
P308 + P313 | IF exposed or concerned: Get medical advice/attention. |
P309 + P311 | IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician. |
P332 + P313 | IF SKIN irritation occurs: Get medical advice/attention. |
P333 + P313 | IF SKIN irritation or rash occurs: Get medical advice/attention. |
P335 + P334 | Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages. |
P337 + P313 | IF eye irritation persists: Get medical advice/attention. |
P342 + P311 | IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician. |
P370 + P376 | In case of fire: Stop leak if safe to Do so. |
P370 + P378 | In case of fire: |
P370 + P380 | In case of fire: Evacuate area. |
P370 + P380 + P375 | In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion. |
P371 + P380 + P375 | In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion. |
Storage | |
Code | Phrase |
P401 | |
P402 | Store in a dry place. |
P403 | Store in a well-ventilated place. |
P404 | Store in a closed container. |
P405 | Store locked up. |
P406 | Store in corrosive resistant/ container with a resistant inner liner. |
P407 | Maintain air gap between stacks/pallets. |
P410 | Protect from sunlight. |
P411 | |
P412 | Do not expose to temperatures exceeding 50 oC/ 122 oF. |
P413 | |
P420 | Store away from other materials. |
P422 | |
P402 + P404 | Store in a dry place. Store in a closed container. |
P403 + P233 | Store in a well-ventilated place. Keep container tightly closed. |
P403 + P235 | Store in a well-ventilated place. Keep cool. |
P410 + P403 | Protect from sunlight. Store in a well-ventilated place. |
P410 + P412 | Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF. |
P411 + P235 | Keep cool. |
Disposal | |
Code | Phrase |
P501 | Dispose of contents/container to ... |
P502 | Refer to manufacturer/supplier for information on recovery/recycling |
Physical hazards | |
Code | Phrase |
H200 | Unstable explosive |
H201 | Explosive; mass explosion hazard |
H202 | Explosive; severe projection hazard |
H203 | Explosive; fire, blast or projection hazard |
H204 | Fire or projection hazard |
H205 | May mass explode in fire |
H220 | Extremely flammable gas |
H221 | Flammable gas |
H222 | Extremely flammable aerosol |
H223 | Flammable aerosol |
H224 | Extremely flammable liquid and vapour |
H225 | Highly flammable liquid and vapour |
H226 | Flammable liquid and vapour |
H227 | Combustible liquid |
H228 | Flammable solid |
H229 | Pressurized container: may burst if heated |
H230 | May react explosively even in the absence of air |
H231 | May react explosively even in the absence of air at elevated pressure and/or temperature |
H240 | Heating may cause an explosion |
H241 | Heating may cause a fire or explosion |
H242 | Heating may cause a fire |
H250 | Catches fire spontaneously if exposed to air |
H251 | Self-heating; may catch fire |
H252 | Self-heating in large quantities; may catch fire |
H260 | In contact with water releases flammable gases which may ignite spontaneously |
H261 | In contact with water releases flammable gas |
H270 | May cause or intensify fire; oxidizer |
H271 | May cause fire or explosion; strong oxidizer |
H272 | May intensify fire; oxidizer |
H280 | Contains gas under pressure; may explode if heated |
H281 | Contains refrigerated gas; may cause cryogenic burns or injury |
H290 | May be corrosive to metals |
Health hazards | |
Code | Phrase |
H300 | Fatal if swallowed |
H301 | Toxic if swallowed |
H302 | Harmful if swallowed |
H303 | May be harmful if swallowed |
H304 | May be fatal if swallowed and enters airways |
H305 | May be harmful if swallowed and enters airways |
H310 | Fatal in contact with skin |
H311 | Toxic in contact with skin |
H312 | Harmful in contact with skin |
H313 | May be harmful in contact with skin |
H314 | Causes severe skin burns and eye damage |
H315 | Causes skin irritation |
H316 | Causes mild skin irritation |
H317 | May cause an allergic skin reaction |
H318 | Causes serious eye damage |
H319 | Causes serious eye irritation |
H320 | Causes eye irritation |
H330 | Fatal if inhaled |
H331 | Toxic if inhaled |
H332 | Harmful if inhaled |
H333 | May be harmful if inhaled |
H334 | May cause allergy or asthma symptoms or breathing difficulties if inhaled |
H335 | May cause respiratory irritation |
H336 | May cause drowsiness or dizziness |
H340 | May cause genetic defects |
H341 | Suspected of causing genetic defects |
H350 | May cause cancer |
H351 | Suspected of causing cancer |
H360 | May damage fertility or the unborn child |
H361 | Suspected of damaging fertility or the unborn child |
H361d | Suspected of damaging the unborn child |
H362 | May cause harm to breast-fed children |
H370 | Causes damage to organs |
H371 | May cause damage to organs |
H372 | Causes damage to organs through prolonged or repeated exposure |
H373 | May cause damage to organs through prolonged or repeated exposure |
Environmental hazards | |
Code | Phrase |
H400 | Very toxic to aquatic life |
H401 | Toxic to aquatic life |
H402 | Harmful to aquatic life |
H410 | Very toxic to aquatic life with long-lasting effects |
H411 | Toxic to aquatic life with long-lasting effects |
H412 | Harmful to aquatic life with long-lasting effects |
H413 | May cause long-lasting harmful effects to aquatic life |
H420 | Harms public health and the environment by destroying ozone in the upper atmosphere |
Sorry,this product has been discontinued.
Home
* Country/Region
* Quantity Required :
* Cat. No.:
* CAS No :
* Product Name :
* Additional Information :