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Chemical Structure| 316-46-1 Chemical Structure| 316-46-1
Chemical Structure| 316-46-1

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5-Fluorouridine is a metabolite of 5-fluorouracil with anticancer activity and cytotoxic activity. 5-fluorouridine inhibits rRNA synthesis of human colon carcinoma cells. 5-Fluorouridine exhibits cytotoxic effect on growth of L1210 cells with an IC50 of 2 nM. 5-Fluorouridine triphosphate acted as a potent competitive inhibitor of VPg uridylylation, the initial step of viral replication.

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Product Details of 5-Fluorouridine

CAS No. :316-46-1
Formula : C9H11FN2O6
M.W : 262.19
SMILES Code : O=C1NC(C(F)=CN1[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)=O
MDL No. :MFCD00036832
InChI Key :FHIDNBAQOFJWCA-UAKXSSHOSA-N
Pubchem ID :9427

Safety of 5-Fluorouridine

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P280-P305+P351+P338

Application In Synthesis of 5-Fluorouridine

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 316-46-1 ]
 

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