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Chemical Structure| 5116-24-5 Chemical Structure| 5116-24-5

Structure of 5116-24-5

Chemical Structure| 5116-24-5

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5-Hydroxymethyl-2'-deoxyuridine is a nucleoside analogue that effectively inhibits the proliferation of various human leukemia cell lines, with IC50 values ranging from 1.7 to 5.8 μM. This compound prolongs the survival of mice in leukemia models, suitable for related research.

Synonyms: 5-(Hydroxymethyl)-2’-deoxyuridine

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Product Details of 5-Hydroxymethyl-2'-deoxyuridine

CAS No. :5116-24-5
Formula : C10H14N2O6
M.W : 258.23
SMILES Code : O=C1NC(C(CO)=CN1[C@@H]2O[C@H](CO)[C@@H](O)C2)=O
Synonyms :
5-(Hydroxymethyl)-2’-deoxyuridine
MDL No. :MFCD00047489
InChI Key :IPAVKOYJGUMINP-XLPZGREQSA-N
Pubchem ID :91541

Safety of 5-Hydroxymethyl-2'-deoxyuridine

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Isoform Comparison

Biological Activity

Description
5-Hydroxymethyl-2'-deoxyuridine (HMdU) is a nucleoside analog known for inhibiting the replication of various human leukemia cell lines, exhibiting IC50 values ranging from 1.7 to 5.8 μM. HMdU also extends the lifespan of mice with L1210 leukemia. It is applicable for investigating cell replication and leukemia[1][2][3].

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3.87mL

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0.39mL

19.36mL

3.87mL

1.94mL

38.73mL

7.75mL

3.87mL

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