[ CAS No. 504-74-5 ] {[proInfo.proName]}

Name: 504-74-5|Imidazolidine|90% in H2O
Brand: Ambeed
SKU: A318836
Price: 5.0 USD
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Quality Control of [ 504-74-5 ]

COA NMR CNMR HPLC LC-MS

Related Doc. of [ 504-74-5 ]

SDS Specification

Alternatived Products of [ 504-74-5 ]

Product Details of [ 504-74-5 ]

CAS No. :	504-74-5	MDL No. :	MFCD19216513
Formula :	C₃H₈N₂	Boiling Point :	-
Linear Structure Formula :	-	InChI Key :	WRYCSMQKUKOKBP-UHFFFAOYSA-N
M.W :	72.11	Pubchem ID :	449488
Synonyms :

Calculated chemistry of [ 504-74-5 ]

Physicochemical Properties

Num. heavy atoms :	5
Num. arom. heavy atoms :	0
Fraction Csp3 :	1.0
Num. rotatable bonds :	0
Num. H-bond acceptors :	2.0
Num. H-bond donors :	2.0
Molar Refractivity :	27.85
TPSA :	24.06 Å²

Pharmacokinetics

GI absorption :	Low
BBB permeant :	No
P-gp substrate :	No
CYP1A2 inhibitor :	No
CYP2C19 inhibitor :	No
CYP2C9 inhibitor :	No
CYP2D6 inhibitor :	No
CYP3A4 inhibitor :	No
Log Kp (skin permeation) :	-7.28 cm/s

Lipophilicity

Log Po/w (iLOGP) :	1.14
Log Po/w (XLOGP3) :	-0.76
Log Po/w (WLOGP) :	-1.62
Log Po/w (MLOGP) :	-0.62
Log Po/w (SILICOS-IT) :	0.78
Consensus Log Po/w :	-0.22

Druglikeness

Lipinski :	0.0
Ghose :	None
Veber :	0.0
Egan :	0.0
Muegge :	2.0
Bioavailability Score :	0.55

Water Solubility

Log S (ESOL) :	0.19
Solubility :	112.0 mg/ml ; 1.55 mol/l
Class :	Highly soluble
Log S (Ali) :	0.73
Solubility :	389.0 mg/ml ; 5.4 mol/l
Class :	Highly soluble
Log S (SILICOS-IT) :	-0.67
Solubility :	15.3 mg/ml ; 0.212 mol/l
Class :	Soluble

Medicinal Chemistry

PAINS :	0.0 alert
Brenk :	0.0 alert
Leadlikeness :	1.0
Synthetic accessibility :	1.09

Safety of [ 504-74-5 ]

Signal Word:	Danger	Class:	8
Precautionary Statements:	P261-P273-P280-P305+P351+P338-P310	UN#:	3267
Hazard Statements:	H314-H317-H334-H361-H402	Packing Group:	Ⅲ
GHS Pictogram:

Application In Synthesis of [ 504-74-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

Upstream synthesis route of [ 504-74-5 ]
Downstream synthetic route of [ 504-74-5 ]

[ 504-74-5 ] Synthesis Path-Upstream 1~5

1
[ 51-46-7 ]
[ 504-74-5 ]
[ 280-29-5 ]
[ 100-97-0 ]

Reference： [1] Tetrahedron Letters, 2008, vol. 49, # 13, p. 2154 - 2158

2
[ 50-00-0 ]
[ 107-15-3 ]
[ 504-74-5 ]

Yield	Reaction Conditions	Operation in experiment
71%	With magnesium sulfate; potassium carbonate In chloroform at 20℃; for 18 h;	[0044] Procedure for preparation of imidazolidine: Ethyl enediamine (1 g, 16.6 mmol) was added to a suspension of paraformaldehyde (0.49 g 16.6 mmol), K₂CO₃ (8.0 g, 58.3 mmol) and MgSO i (7.0 g, 5S.8 mmol) in CHC1:,(3O mL)under argon at room temperature. After stining for 18 h, the mixture was filtered, evaporated and purified by column chromatography on neutral alumina, eluting with CHCl₃-MeOH (2:8), to give the imidazolidine (71 percent).

Reference： [1] Patent: WO2008/83038, 2008, A1, . Location in patent: Page/Page column 25
[2] Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1987, p. 1695 - 1700
[3] Synthesis, 1998, # 10, p. 1463 - 1466

3
[ 51-46-7 ]
[ 504-74-5 ]
[ 280-29-5 ]
[ 100-97-0 ]

Reference： [1] Tetrahedron Letters, 2008, vol. 49, # 13, p. 2154 - 2158

4
[ 1367520-68-0 ]
[ 107-15-3 ]
[ 504-74-5 ]
[ 1367903-87-4 ]

Reference： [1] Synthetic Communications, 2012, vol. 42, # 8, p. 1200 - 1210

5
[ 50-00-0 ]
[ 18299-54-2 ]
[ 504-74-5 ]

Reference： [1] Makromolekulare Chemie, 1955, vol. 17, p. 77,105

[ 504-74-5 ] Synthesis Path-Downstream 1~22

1
[ 504-74-5 ]
[ 98-88-4 ]
[ 49738-18-3 ]

Reference： [1]Journal of the Chemical Society. Perkin transactions II,1987,p. 1695 - 1700
[2]Makromolekulare Chemie,1955,vol. 17,p. 77,105
[3]Synthesis,1998,p. 1463 - 1466

2
[ 504-74-5 ]
[ 103-71-9 ]
imidazolidine-1,3-dicarboxylic acid-dianilide [ No CAS ]

Reference： [1]Makromolekulare Chemie,1955,vol. 17,p. 77,105

3
[ 504-74-5 ]
[ 51-46-7 ]
[ 107-15-3 ]

Reference： [1]Makromolekulare Chemie,1955,vol. 17,p. 77,105

4
[ 50-00-0 ]
[ 18299-54-2 ]
[ 504-74-5 ]

Reference： [1]Makromolekulare Chemie,1955,vol. 17,p. 77,105

5
[ 504-74-5 ]
[ 3282-30-2 ]
[ 116046-91-4 ]

Reference： [1]Journal of the Chemical Society. Perkin transactions II,1987,p. 1695 - 1700

6
[ 504-74-5 ]
[ 123476-78-8 ]
[ 123476-97-1 ]
[ 130719-54-9 ]

Reference： [1]Archiv der Pharmazie,1990,vol. 323,p. 571 - 578

7
[ 50-00-0 ]
[ 107-15-3 ]
[ 504-74-5 ]

Yield	Reaction Conditions	Operation in experiment
71%	With magnesium sulfate; potassium carbonate; In chloroform; at 20℃; for 18.0h;	[0044] Procedure for preparation of imidazolidine: Ethyl enediamine (1 g, 16.6 mmol) was added to a suspension of paraformaldehyde (0.49 g 16.6 mmol), K2CO3 (8.0 g, 58.3 mmol) and MgSO i (7.0 g, 5S.8 mmol) in CHC1:,(3O mL)under argon at room temperature. After stining for 18 h, the mixture was filtered, evaporated and purified by column chromatography on neutral alumina, eluting with CHCl3-MeOH (2:8), to give the imidazolidine (71 %).

Reference： [1]Patent: WO2008/83038,2008,A1 .Location in patent: Page/Page column 25
[2]Journal of the Chemical Society. Perkin transactions II,1987,p. 1695 - 1700
[3]Synthesis,1998,p. 1463 - 1466

8
[ 504-74-5 ]
[ 24424-99-5 ]
Imidazolidine-1,3-dicarboxylic acid di-tert-butyl ester [ No CAS ]

Reference： [1]Synthesis,1998,p. 1463 - 1466

9
[ 504-74-5 ]
[ 79-03-8 ]
[ 49738-16-1 ]

Reference： [1]Synthesis,1998,p. 1463 - 1466

10
[ 504-74-5 ]
[ 79-22-1 ]
Imidazolidine-1,3-dicarboxylic acid dimethyl ester [ No CAS ]

Reference： [1]Synthesis,1998,p. 1463 - 1466

11
[ 504-74-5 ]
[ 131838-93-2 ]
[ 131839-31-1 ]

Yield	Reaction Conditions	Operation in experiment
	In methanol; chloroform; mineral oil;	EXAMPLE 37 To a solution of 2-(cycanoimino)<strong>[504-74-5]imidazolidine</strong> (0.28 g) in dimeythyl sulfoxide (10 ml) was added 60% sodium hydride dispersed in mineral oil (0.1 g) and the mixture was stirred at room temperature for 25 minutes. After an addition of N-(4-chloro-2-butynyl)-2-cyclohexyl-2-hydroxy-2-phenylacetamide (0.40 g), the mixture was stirred at the same temperature for further 45 minutes and then quenched with cold water (50 ml). The mixture was extracted with ethyl acetate (50 ml*3). The combined extracts were washed with sodium chloride aqueous solution, dried over magnesium sulfate, and evaporated in vacuo. The residue was purified by column chromatography on silica gel with a mixture of chloroform and methanol (20:1) as an eluent to give N-[4-{2-(cyanoimino)-1-imidazolidinyl}-2-butynyl]-2-cyclohexyl-2-hydroxy-2-phenylacetamide (0.37 g). mp: 207 to 210 C. IR (Nujol): 3300, 2170, 1650 cm-1. NMR (CD3 OD, delta): 0.92-1.90 (10H, m), 2.19-2.56 (1H, m), 3.21-3.40 (4H, m), 3.83-4.04 (4H, m), 7.12-7.43 (3H, m), 7.43-7.70 (2H, m). Mass: 393, 310, 189.

Reference： [1]Patent: US5066680,1991,A

Yield	Reaction Conditions	Operation in experiment
		EXAMPLE 44 Preparation of 1-(benzyloxy)-2-[(2,6-dichlorophenyl)imino] imidazolidine 25 ml. of 50% strength tetrafluoroboric acid are added to 24.6 g. of O-benzylhydroxylamine, whereupon the temperature rises to 70. A solution of 13 ml. of aziridine in 13 ml. of water is added to this solution at 50 at a rate such that the temperature does not exceed 60. At the end of the exothermic reaction, the mixture is cooled to 5, and a solution of 56 g. of potassium carbonate in 100 ml. of water is added. 60 ml. of toluene and 35 ml. of (2,6-dichlorophenyl)imidocarbonyl chloride are added, while stirring vigorously. The temperature rises to 43, carbon dioxide being evolved. The reaction mixture is further stirred for 90 minutes and 150 ml. of hexane and 200 ml. of water are then added. The crystalline mass is washed carefully with water and hexane and dried overnight under reduced pressure. The dried substance is recrystallized from isopropyl ether, whereupon 1-(benzyloxy)-2-[(2,6-dichlorophenyl)imino] imidazolidine, m.p. 115-117, is obtained.

13
[ 504-74-5 ]
[ 84858-00-4 ]
[ 274-95-3 ]
8-(2-Bromo-6-fluorophenyl)-2,3,5,8-tetrahydro-imidazo[1,2-a]pyrimidine [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	With sodium hydroxide; In hydrogenchloride; ethanol;	EXAMPLE 2 8-(2-Bromo-6-fluorophenyl)-2,3,5,8-tetrahydro-<strong>[274-95-3]imidazo[1,2-a]pyrimidine</strong> STR6 A quantity of 8.9 gm of 1-propargyl-2-(2-bromo-6-fluorophenylimino)-imidazolidine was refluxed in 60 ml of absolute ethanol for about 11 hours. The solvent was then removed in vacuo, and the remaining residue, consisting of the starting imidazolidine, 1-(2-bromo-6-fluorophenyl)-2,3,5,6-tetrahydro-2-methylene-1H-imidazo[1,2-a]imidazole, and the desired <strong>[274-95-3]imidazo[1,2-a]pyrimidine</strong>, was dissolved in dilute 1 N hydrochloric acid. Then, at increasing pH values (rendered alkaline with 2 N NaOH), the first two compounds mentioned were removed by fractional extraction with ethyl acetate. As soon as the aqueous solution contained only the new <strong>[274-95-3]imidazo[1,2-a]pyrimidine</strong> (checked by thin layer chromatography), it was rendered further alkaline, and the new compound was extracted with ethyl acetate. Yield: 0.9 gm (10.1percent of theory) after evaporation in vacuo; Melting point: 116°-120° C.

Reference： [1]Patent: US4438118,1984,A

14
[ 504-74-5 ]
1-propargyl-2-(2,6-dichlorophenylimino)-imidazolidine [ No CAS ]
[ 84857-90-9 ]

Yield	Reaction Conditions	Operation in experiment
	With sodium hydroxide; In hydrogenchloride; ethanol;	EXAMPLE 1 1-(2,6-Dichlorophenyl)-2,3,5,6-tetrahydro-2-methylene-1H-imidazo[1,2-a]imidazole STR4 An amount of 5.4 gm of 1-propargyl-2-(2,6-dichlorophenylimino)-<strong>[504-74-5]imidazolidine</strong> was refluxed in 40 ml of ethanol for 10 hours, under stirring. The reaction mixture was then evaporated to dryness in vacuo. The residue was dissolved in 1N HCl, and the resulting solution was fractionally extracted with ether at increasing pH values (rendered alkaline with 2N NaOH). The starting <strong>[504-74-5]imidazolidine</strong> was separated as the first compound (checked by thin layer chromatography). As soon as it had been quantitatively removed, the new imidazo[1,2-a]imidazole derivative was fractionally extracted with ether, as the pH values were progressively increased (slowly rendered alkaline with 2N NaOH in stages; checked by thin layer chromatography).

Reference： [1]Patent: US4454149,1984,A

15
[ 504-74-5 ]
1-propargyl-2-(2,6-dichlorophenylimino)-imidazolidine [ No CAS ]
8-(2,6-Dichlorophenyl)-2,3,5,8-tetrahydro-imidazo[1,2-a]pyrimidine [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	With sodium hydroxide; In hydrogenchloride; ethanol;	EXAMPLE 1 8-(2,6-Dichlorophenyl)-2,3,5,8-tetrahydro-imidazo[1-2-a]pyrimidine STR5 An amount of 5.4 gm of 1-propargyl-2-(2,6-dichlorophenylimino)-<strong>[504-74-5]imidazolidine</strong> was refluxed in 40 ml of ethanol for ten hours, under stirring. The reaction mixture was then evaporated to dryness in vacuo. The residue was dissolved in 1 N hydrochloric acid, and the solution obtained was fractionally extracted with ether at increasing pH values (rendered alkaline with 2 N NaOH). The starting <strong>[504-74-5]imidazolidine</strong> and an isomeric compound of Formula IV were separated by extraction at lower pH values (monitored by thin layer chromatography). As soon as the desired imidazo[1,2-a]pyrimidine was present in pure form in the aqueous phase, this was rendered further alkaline with 2 N sodium hydroxide solution, and the new compound was extracted with ether (the ether fractions being monitored by thin layer chromatography). After the ether was removed in vacuo, a yield of 1.1 gm was obtained, corresponding to 20.5% of theory. Melting point: 156-166 C. The hydrobromide melted at 203-204 C.

Reference： [1]Patent: US4438118,1984,A

16
[ 504-74-5 ]
1-propargyl-2-(2-bromo-6-fluorophenylimino)-imidazolidine [ No CAS ]
1-(2-bromo-6-fluorophenyl)-2,3,5,6-tetrahydro-2-methylene-1H-imidazo[1,2-a]imidazole [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	With sodium hydroxide; In hydrogenchloride; ethanol;	EXAMPLE 2 1-(2-Bromo-6-fluorophenyl)-2,3,5,6-tetrahydro-2-methylene-1H-imidazo[1,2-a]imidazole STR5 A quantity of 8.9 gm of 1-propargyl-2-(2-bromo-6-fluorophenylimino)-<strong>[504-74-5]imidazolidine</strong> was refluxed in 60 ml of absolute ethanol for about 11 hours. Then the solvent was eliminated in vacuo, and the remaining residue was dissolved in dilute (approximately 1N) hydrochloric acid. The <strong>[504-74-5]imidazolidine</strong> derivative used (identified by thin layer chromatography) was then eliminated by fractional extraction with ethyl acetate at increasing pH values (rendered alkaline with 2N NaOH). As soon as the starting <strong>[504-74-5]imidazolidine</strong> has been quantitatively removed, the imidazo[1,2-a]imidazole derivative according to the invention was extracted as the pH values increased still further (carefully rendered alkaline with 2N NaOH in stages).

Reference： [1]Patent: US4454149,1984,A

17
[ 504-74-5 ]
[ 110-52-1 ]
2BF₄^(1-)*C₁₁H₂₂N₂⁽²⁺⁾ [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	With potassium carbonate; potassium tetrafluoroborate; In acetonitrile; for 6.0h;Heating / reflux;	The prophetic examples in Table 2 have been carried out as described in Example 4 using different cyclic amines and alkylating agents.

Reference： [1]Patent: US2007/49750,2007,A1 .Location in patent: Page/Page column 6; 10

18
[ 51-46-7 ]
[ 504-74-5 ]
[ 280-29-5 ]
[ 100-97-0 ]
1,3,6,8-tetraazatricyclo[4.3.1.1^3,8]undecane [ No CAS ]

Reference： [1]Tetrahedron Letters,2008,vol. 49,p. 2154 - 2158

19
[ 1367520-68-0 ]
[ 107-15-3 ]
[ 504-74-5 ]
[ 1367903-87-4 ]

Reference： [1]Synthetic Communications,2012,vol. 42,p. 1200 - 1210

20
[ 504-74-5 ]
[ 50-00-0 ]
[ 96-76-4 ]
[ 936741-84-3 ]

Reference： [1]RSC Advances,2015,vol. 5,p. 53161 - 53171

21
[ 504-74-5 ]
[ 50-00-0 ]
[ 871-84-1 ]
1,3-di(nona-2,8-diyn-1-yl)imidazolidine [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
62%	With copper(l) chloride; In toluene; at 100℃; for 8.0h;Inert atmosphere;	General procedure: Toluene (5 mL), secondary diamine (2a,b or 4-c) (1 mmol), paraformaldehyde or 4-fluorobenzaldehyde (2 mmol), alpha,omega-diacetylene (2 mmol), and CuCl (10 mol.%, 0.1 mg) were placed under argon into a Schlenk flask (10 mL) mounted on a magnetic stirrer, and the mixture was stirred for 8 h at 100 C under argon atmosphere.The resulting mixture was cooled, filtered through a layer ofsilica gel, dried over Na2SO4. The solvent was evaporated. The product was purified by column chromatography, the eluent is indicated in the description of the compound.

Reference： [1]Russian Chemical Bulletin,2019,vol. 68,p. 1407 - 1413
Izv. Akad. Nauk, Ser. Khim.,2019,p. 1407 - 1413,7

22
[ 504-74-5 ]
[ 50-00-0 ]
[ 2396-63-6 ]
1,3-di(octa-2,7-diyn-1-yl)imidazolidine [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
51%	With copper(l) chloride; In toluene; at 100℃; for 8.0h;Inert atmosphere;	General procedure: Toluene (5 mL), secondary diamine (2a,b or 4-c) (1 mmol), paraformaldehyde or 4-fluorobenzaldehyde (2 mmol), alpha,omega-diacetylene (2 mmol), and CuCl (10 mol.%, 0.1 mg) were placed under argon into a Schlenk flask (10 mL) mounted on a magnetic stirrer, and the mixture was stirred for 8 h at 100 C under argon atmosphere.The resulting mixture was cooled, filtered through a layer ofsilica gel, dried over Na2SO4. The solvent was evaporated. The product was purified by column chromatography, the eluent is indicated in the description of the compound.

Reference： [1]Russian Chemical Bulletin,2019,vol. 68,p. 1407 - 1413
Izv. Akad. Nauk, Ser. Khim.,2019,p. 1407 - 1413,7

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Code	Phrase
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P321
P322
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P342	If experiencing respiratory symptoms:
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P378
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P401
P402	Store in a dry place.
P403	Store in a well-ventilated place.
P404	Store in a closed container.
P405	Store locked up.
P406	Store in corrosive resistant/ container with a resistant inner liner.
P407	Maintain air gap between stacks/pallets.
P410	Protect from sunlight.
P411
P412	Do not expose to temperatures exceeding 50 oC/ 122 oF.
P413
P420	Store away from other materials.
P422
P402 + P404	Store in a dry place. Store in a closed container.
P403 + P233	Store in a well-ventilated place. Keep container tightly closed.
P403 + P235	Store in a well-ventilated place. Keep cool.
P410 + P403	Protect from sunlight. Store in a well-ventilated place.
P410 + P412	Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF.
P411 + P235	Keep cool.
Disposal
Code	Phrase
P501	Dispose of contents/container to ...
P502	Refer to manufacturer/supplier for information on recovery/recycling

Purity	Size	Price	VIP Price	USA Stock *0-1 Day	Global Stock *5-7 Days	Quantity
{[ item.p_purity ]}	{[ item.pr_size ]}	{[ getRatePrice(item.pr_usd, 1,1) ]} {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate) ]}	{[ getRatePrice(item.pr_usd, 1,1) ]}	Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate) ]} {[ getRatePrice(item.pr_usd,1,item.mem_rate) ]}	{[ item.pr_usastock ]}	Inquiry -	{[ item.pr_chinastock ]}	Inquiry -

Physical hazards
Code	Phrase
H200	Unstable explosive
H201	Explosive; mass explosion hazard
H202	Explosive; severe projection hazard
H203	Explosive; fire, blast or projection hazard
H204	Fire or projection hazard
H205	May mass explode in fire
H220	Extremely flammable gas
H221	Flammable gas
H222	Extremely flammable aerosol
H223	Flammable aerosol
H224	Extremely flammable liquid and vapour
H225	Highly flammable liquid and vapour
H226	Flammable liquid and vapour
H227	Combustible liquid
H228	Flammable solid
H229	Pressurized container: may burst if heated
H230	May react explosively even in the absence of air
H231	May react explosively even in the absence of air at elevated pressure and/or temperature
H240	Heating may cause an explosion
H241	Heating may cause a fire or explosion
H242	Heating may cause a fire
H250	Catches fire spontaneously if exposed to air
H251	Self-heating; may catch fire
H252	Self-heating in large quantities; may catch fire
H260	In contact with water releases flammable gases which may ignite spontaneously
H261	In contact with water releases flammable gas
H270	May cause or intensify fire; oxidizer
H271	May cause fire or explosion; strong oxidizer
H272	May intensify fire; oxidizer
H280	Contains gas under pressure; may explode if heated
H281	Contains refrigerated gas; may cause cryogenic burns or injury
H290	May be corrosive to metals
Health hazards
Code	Phrase
H300	Fatal if swallowed
H301	Toxic if swallowed
H302	Harmful if swallowed
H303	May be harmful if swallowed
H304	May be fatal if swallowed and enters airways
H305	May be harmful if swallowed and enters airways
H310	Fatal in contact with skin
H311	Toxic in contact with skin
H312	Harmful in contact with skin
H313	May be harmful in contact with skin
H314	Causes severe skin burns and eye damage
H315	Causes skin irritation
H316	Causes mild skin irritation
H317	May cause an allergic skin reaction
H318	Causes serious eye damage
H319	Causes serious eye irritation
H320	Causes eye irritation
H330	Fatal if inhaled
H331	Toxic if inhaled
H332	Harmful if inhaled
H333	May be harmful if inhaled
H334	May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335	May cause respiratory irritation
H336	May cause drowsiness or dizziness
H340	May cause genetic defects
H341	Suspected of causing genetic defects
H350	May cause cancer
H351	Suspected of causing cancer
H360	May damage fertility or the unborn child
H361	Suspected of damaging fertility or the unborn child
H361d	Suspected of damaging the unborn child
H362	May cause harm to breast-fed children
H370	Causes damage to organs
H371	May cause damage to organs
H372	Causes damage to organs through prolonged or repeated exposure
H373	May cause damage to organs through prolonged or repeated exposure
Environmental hazards
Code	Phrase
H400	Very toxic to aquatic life
H401	Toxic to aquatic life
H402	Harmful to aquatic life
H410	Very toxic to aquatic life with long-lasting effects
H411	Toxic to aquatic life with long-lasting effects
H412	Harmful to aquatic life with long-lasting effects
H413	May cause long-lasting harmful effects to aquatic life
H420	Harms public health and the environment by destroying ozone in the upper atmosphere

[ CAS No. 504-74-5 ] {[proInfo.proName]}

Quality Control of [ 504-74-5 ]

Related Doc. of [ 504-74-5 ]

Product Details of [ 504-74-5 ]

Calculated chemistry of [ 504-74-5 ]

Physicochemical Properties

Pharmacokinetics

Lipophilicity

Druglikeness

Water Solubility

Medicinal Chemistry

Safety of [ 504-74-5 ]

Application In Synthesis of [ 504-74-5 ]

[ 504-74-5 ] Synthesis Path-Upstream 1~5

[ 504-74-5 ] Synthesis Path-Downstream 1~22

Precautionary Statements-General

Prevention

Response

Storage

Disposal

Physical hazards

Health hazards

Environmental hazards

Inquiry