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Chemical Structure| 5089-33-8 Chemical Structure| 5089-33-8

Structure of 5089-33-8

Chemical Structure| 5089-33-8

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Product Details of [ 5089-33-8 ]

CAS No. :5089-33-8
Formula : C12H22BrNSi2
M.W : 316.38
SMILES Code : C[Si](N(C1=CC=C(Br)C=C1)[Si](C)(C)C)(C)C
MDL No. :MFCD00191840
InChI Key :YJYMZGDBOMZWSR-UHFFFAOYSA-N
Pubchem ID :4092620

Safety of [ 5089-33-8 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 5089-33-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 5089-33-8 ]

[ 5089-33-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 681-84-5 ]
  • [ 5089-33-8 ]
  • [ 33976-43-1 ]
YieldReaction ConditionsOperation in experiment
13.6 g To a 2000 mL round bottom flask under nitrogen was added THF (700 mL) and magnesium particles (11.8 g, 485 mmol) was added to the mixture, and 1,2-dibromoethane (2 drop)And stirred at 45 & lt; 0 & gt; C for 20 minutes.The compound 74-3 (70 g, 220 mmol) obtained previously was added to the reaction solution at the same temperature (45 DEG C) is slowly added and stirred at reflux for 3 hours.The reaction was cooled to room temperature (25 deg C) (compound 74-2)A solution of tetramethylorthosilicate (32.6 mL, 220 mmol / 60 mL of THF) is slowly added dropwise.After stirring at room temperature (25 deg C) for 30 min (Compound 98-6)The saturated NH4Cl aqueous solution is added in excess and stirred overnight.The reaction mixture was stirred with EA, and the organic layer was separated,It is dried over MgSO4 and concentrated under reduced pressure.The obtained concentrate was purified by column chromatography (EA: hexane = 1: 12) using silica gel,The product 98-5 (13.6 g, total of 29 wt% in three steps) was obtained by purification.
 

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