Alternatived Products of [ 52188-11-1 ]
Product Details of [ 52188-11-1 ]
CAS No. : | 52188-11-1 |
MDL No. : | MFCD00688358 |
Formula : |
C9H7NO5S
|
Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | MQAZHTHFEBUHCD-UHFFFAOYSA-N |
M.W : |
241.22
|
Pubchem ID : | 818753 |
Synonyms : |
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Application In Synthesis of [ 52188-11-1 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 52188-11-1 ]
- 1
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[ 52188-11-1 ]
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[ 42854-62-6 ]
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[ 474900-01-1 ]
- 2
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[ 52188-11-1 ]
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[ 1738-76-7 ]
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[ 474900-02-2 ]
- 3
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[ 926224-90-0 ]
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[ 52188-11-1 ]
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[ 1221971-28-3 ]
Yield | Reaction Conditions | Operation in experiment |
75% |
With tributyl-amine; 2-chloro-1-methyl-pyridinium iodide In dichloromethane for 1h; Reflux; |
|
Reference:
[1]Location in patent: scheme or table
Wang, Jane; Limburg, David; Carter, Jeff; Mbalaviele, Gabriel; Gierse, James; Vazquez, Michael
[Bioorganic and Medicinal Chemistry Letters, 2010, vol. 20, # 5, p. 1604 - 1609]
- 4
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[ 52188-11-1 ]
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[ 538-51-2 ]
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trans-2-(-2-oxo-1,4-diphenylazetidin-3-yl)benzo[d]isothiazol-3(2H)-one-1,1-dioxide
[ No CAS ]
Yield | Reaction Conditions | Operation in experiment |
86% |
With 2-chloro-1-methyl-pyridinium iodide; triethylamine In dichloromethane at 100℃; for 0.166667h; Microwave irradiation; diastereoselective reaction; |
3 General procedure B, cycloaddition
General procedure: A microwave vial wascharged with dichloromethane the appropriate imine (1.0 equiv),saccharinyl acetic acid (1.0 equiv), Mukaiyama’s salt (1.05 equiv)and triethylamine (2 equiv). The mixture was heated for 10 minin the microwave at 100 C. After the reaction, the mixture wasconcentrated in vacuo and puried on a preparative LCMS. WatersX-Bridge 30 mm 150 mm C18 column; gradient, CH3CN:H2O(0.1% TFA). Fractions containing the product were automaticallycollected based on observed mass and UV-signal after which theywere lyophilized to obtain the pure products. |
- 5
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[ 22179-78-8 ]
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[ 52188-11-1 ]
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2‐[3‐(4‐fluorophenyl)‐1,2,4‐oxadiazol‐5‐yl]methyl}benzo[d]isothiazol‐3(2H)‐one 1,1‐dioxide
[ No CAS ]
Yield | Reaction Conditions | Operation in experiment |
52% |
Stage #1: 4-fluoro-N'-hydroxybenzimidamide; 2-(1,1-dioxido-3-oxobenzo[d]isothiazol-2(3H)-yl)acetic acid With triethylamine In ethyl acetate for 0.5h; Inert atmosphere;
Stage #2: With 1-propanephosphonic acid cyclic anhydride In ethyl acetate Inert atmosphere; |
|
Reference:
[1]Angeli, Andrea; Arifuddin, Mohammed; Chinchilli, Krishna K.; Danaboina, Srikanth; Nanduri, Srinivas; Royyala, Venkata N.; Singh, Priti; Supuran, Claudiu T.; Thacker, Pavitra S.
[Archiv der Pharmazie, 2022]
- 6
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[ 52188-11-1 ]
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[ 19227-14-6 ]
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2‐[3‐(4‐bromophenyl)‐1,2,4‐oxadiazol‐5‐yl]methyl}benzo[d]isothiazol‐3(2H)‐one 1,1‐dioxide
[ No CAS ]
Yield | Reaction Conditions | Operation in experiment |
56% |
Stage #1: 2-(1,1-dioxido-3-oxobenzo[d]isothiazol-2(3H)-yl)acetic acid; 4-bromo-N'-hydroxybenzimidamide With triethylamine In ethyl acetate for 0.5h; Inert atmosphere;
Stage #2: With 1-propanephosphonic acid cyclic anhydride In ethyl acetate Inert atmosphere; |
|
Reference:
[1]Angeli, Andrea; Arifuddin, Mohammed; Chinchilli, Krishna K.; Danaboina, Srikanth; Nanduri, Srinivas; Royyala, Venkata N.; Singh, Priti; Supuran, Claudiu T.; Thacker, Pavitra S.
[Archiv der Pharmazie, 2022]