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Chemical Structure| 53271-46-8 Chemical Structure| 53271-46-8

Structure of 53271-46-8

Chemical Structure| 53271-46-8

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Product Details of [ 53271-46-8 ]

CAS No. :53271-46-8
Formula : C16H16O3S
M.W : 288.36
SMILES Code : O=C(SC1=CC=C(C)C=C1)C2=CC(OC)=CC(OC)=C2
English Name :S-p-Tolyl 3,5-dimethoxybenzothioate

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* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 53271-46-8 ]

[ 53271-46-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 652-29-9 ]
  • [ 53271-46-8 ]
  • [ 1251445-50-7 ]
  • [ 1336931-53-3 ]
YieldReaction ConditionsOperation in experiment
20% With hydridotetakis(triphenylphosphine)rhodium(I); 1,2-bis-(diphenylphosphino)ethane In chlorobenzene for 2h; Inert atmosphere; Reflux; 4.10. Synthesis of 3,5-Dimethoxybenzoyl Fluoride 10 using Subsutituted Pentafluorobenzene, Reaction of 4-Tolylthiopentafluorobenzene (Table 5) General procedure: In a two-necked flask equipped with a reflux condenser were placed S-(4-tolyl) 3,5-dimethoxybenzothioate 9 (0.25 mmol, 72 mg), (4-tolylthio)pentafluorobenzene 13 (0.25 mmol, 72.5 mg), RhH(PPh3)4 (2.5 mol%, 7.2 mg), 1,2-bis(diphenylphosphino)ethane (5 mol%, 5.0 mg) in chlorobenzene (1 mL) under an argon atmosphere, and the solution was stirred under reflux for 2 h. The solvent was removed under reduced pressure, and the residue was purified by flash column chromatography on silica gel giving 3,5-dimethoxybenzoyl fluoride 10 (39.5 mg, 86%) and 1,4-bis(4-tolylthio)-2,3,5,6-tetrafluoro benzene (94.3 mg, 96%) as colorless solid.
 

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