Home Cart 0 Sign in  

[ CAS No. 53668-37-4 ]

{[proInfo.proName]} ,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 53668-37-4
Chemical Structure| 53668-37-4
Structure of 53668-37-4 * Storage: {[proInfo.prStorage]}

Quality Control of [ 53668-37-4 ]

Related Doc. of [ 53668-37-4 ]

SDS
Alternatived Products of [ 53668-37-4 ]
Alternatived Products of [ 53668-37-4 ]

Product Details of [ 53668-37-4 ]

CAS No. :53668-37-4 MDL No. :MFCD03488727
Formula : C12H18N2O2S Boiling Point : -
Linear Structure Formula :- InChI Key :-
M.W :254.35 g/mol Pubchem ID :-
Synonyms :

Safety of [ 53668-37-4 ]

Signal Word:Warning Class:
Precautionary Statements:P233-P260-P261-P264-P271-P280-P302+P352-P304-P304+P340-P305+P351+P338-P312-P321-P332+P313-P337+P313-P340-P362-P403-P403+P233-P405-P501 UN#:
Hazard Statements:H315-H319-H335 Packing Group:
GHS Pictogram:

Application In Synthesis of [ 53668-37-4 ]

  • Downstream synthetic route of [ 53668-37-4 ]

[ 53668-37-4 ] Synthesis Path-Downstream   1~14

  • 1
  • N-cyclohexyl 4-(acetamido)benzenesulfonamide [ No CAS ]
  • [ 53668-37-4 ]
YieldReaction ConditionsOperation in experiment
With hydrogenchloride
With hydrogenchloride
  • 2
  • [ 53668-37-4 ]
  • [ 98-88-4 ]
  • <i>N</i>-benzoyl-sulfanilic acid cyclohexylamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
With pyridine
YieldReaction ConditionsOperation in experiment
42.4%
Sulfanilamid, Cyclohexanol/H2SO4 (3h 70grad);
  • 4
  • [ 53668-37-4 ]
  • [ 105893-07-0 ]
  • 2,2'-diselenobis{benz[p-(N-cyclohexylsulfonamido)]anilide} [ No CAS ]
YieldReaction ConditionsOperation in experiment
55% With pyridine In toluene Heating;
  • 5
  • [ 108-91-8 ]
  • [ 53668-37-4 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: diethyl ether 2: aq.-ethanolic hydrochloric acid
Multi-step reaction with 2 steps 1: aqueous acetone; potassium carbonate 2: aqueous hydrochloric acid
Multi-step reaction with 2 steps 1: pyridine / dichloromethane 2: hydrogen; palladium 10% on activated carbon / 1 h / 2585.81 Torr
  • 6
  • [ 121-60-8 ]
  • [ 53668-37-4 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: diethyl ether 2: aq.-ethanolic hydrochloric acid
Multi-step reaction with 2 steps 1: aqueous acetone; potassium carbonate 2: aqueous hydrochloric acid
  • 7
  • [ 117-34-0 ]
  • [ 53668-37-4 ]
  • N-(4-cyclohexylsulfamoyl-phenyl)-2,2-diphenyl-acetamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride
  • 9
  • [ 54-47-7 ]
  • [ 53668-37-4 ]
  • [ 608523-58-6 ]
YieldReaction ConditionsOperation in experiment
25% 18.B Step B. Step B. Preparation of 6-[4-(Cyclohexylsulfamoyl)phenylazo]pyridoxal-5-phosphate The title material was prepared from 4-amino-N-cyclohexyl-benzenesulfonamide (step A) and pyridoxal-5-phosphate as described in general procedure D, method A. The final productproduct was obtained in 25% yield. 1H NMR (D2O): δ 1.04 (m, SH), 1.41 (d, J=11.0, 1H), 1.54 (d, J=18.3, 4H), 2.31 (s, 3H), 2.69 (m, 1H), 5.56 (s, 2H), 7.83 (d, J=8.0, 2H), 7.93 (d, J=8.2, 2H), 10.27 (s, 1H). 31P NMR (D2O): δ 7.05 (s).
  • 11
  • [ 53668-37-4 ]
  • [ 29745-04-8 ]
  • (1S,4R)-3-((4-(N-cyclohexyl)sulfonylphenyl)carbamoyl)-7-oxa-bicyclo[2.2.1]heptane-2-carboxylic acid [ No CAS ]
YieldReaction ConditionsOperation in experiment
53% In tetrahydrofuran at 20℃; 1.2.6 (1S,4R)-3-((4-(N-cyclohexyl)sulfonylphenyl)carbamoyl)-7-oxa-bicyclo[2.2.1]heptane-2-carboxylic acid (16) General procedure: 1.2 General synthetic procedure for carboxylic acid derivatives 11-17.1Thenorcantharidin 2 (168 mg, 1 mmol)was dissolved in tetrahydrofuran (20 ml) and to the correspondingamine (1.1 equiv) added portionwise (for solids) or dropwise (intetrahydrofuran for liquids). After complete reaction the solid was filtered,or the solvent evaporated (in those cases when no precipitate was evident) andthe desired products purified by flash chromatography, eluting withdichloromethane-methanol (20:1). 1.2.6 (1S,4R)-3-((4-(N-cyclohexyl)sulfonylphenyl)carbamoyl)-7-oxa-bicyclo[2.2.1]heptane-2-carboxylic acid (16) Yield : 53%; white power solid; mp : 146-147; IR(KBr, cm-1) 3304, 3102, 1696, 1328, 1158; 1H-NMR (600MHz, DMSO-d6) δ 11.99 (brs,1 H, COOH), 10.06 (s, 1 H, NH) , 7.67-7.71 (m, 4 H), 4.77 (d, 1 H, J=4.2 Hz),4.65 (d, 1 H, J=4.8 Hz), 3.07 (d, 1 H, J=9.6 Hz), 2.95 (d, 1 H, J=9.6 Hz), 2.87(s, 1 H)1.49-1.70 (m, 8 H), 1.42-1.44 (m, 1 H), 1.08-1,10 (m, 4 H), 1.02 (m, 1H); 13C-NMR (150 MHz, DMSO-d6)δ172.1, 169.9, 142.4, 135.9, 127.3 (2 C), 118.7 (2 C), 78.6, 76.9, 53.4 ,51.9,51.7, 33.2 (2 C), 28.9, 28.4, 24.8, 24.3; HRMS (ESI) 423.1582 for [M+H]+(calcd 423.1584 for C20H27N2O6S).
  • 12
  • [ 98-74-8 ]
  • [ 53668-37-4 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: pyridine / dichloromethane 2: hydrogen; palladium 10% on activated carbon / 1 h / 2585.81 Torr
  • 13
  • [ 63-74-1 ]
  • [ 108-93-0 ]
  • [ 53668-37-4 ]
YieldReaction ConditionsOperation in experiment
56% With bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; caesium carbonate In tert-Amyl alcohol at 150℃; for 24h; Inert atmosphere; Schlenk technique;
56% With bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; caesium carbonate In tert-Amyl alcohol at 120℃; for 12h; Inert atmosphere; Schlenk technique; 22 4-amino-N- (cyclohexyl) benzenesulfonamide Under nitrogen, 4-aminobenzenesulfonamide (172 mg, 1 mmol), [Cp * IrCl2] 2 (8 mg, 0.01 mmol, 1Mol%), cesium carbonate (65 mg, 0.2 mmol), cyclohexanol (200 mg, 2 mmol), t-amyl alcohol (1.0 mL)Was added to a 25 mL Schlenk reaction flask. The mixture was reacted at 150 ° C for 24 hours, then cooled to room temperature,The solvent was removed under vacuum. The purified target was then purified by column chromatography (developing solvent: ethyl acetate / n-hexane)The yield of the compound was 56%.
  • 14
  • [ 53668-37-4 ]
  • N-cyclohexyl-4-[(3,5-diamino-1-benzoyl-1H-pyrazol-4-yl)diazenyl]benzenesulfonamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1.1: sodium nitrite; hydrogenchloride / water / Cooling with ice 1.2: 2 h / Cooling with ice 2.1: 1,4-dioxane / Reflux
Historical Records

Related Functional Groups of
[ 53668-37-4 ]

Sulfamides

Chemical Structure| 61886-26-8

[ 61886-26-8 ]

N-Cyclohexyl 3-aminobenzenesulfonamide

Similarity: 0.98

Chemical Structure| 24224-95-1

[ 24224-95-1 ]

N-(Adamantan-1-yl)-4-aminobenzenesulfonamide

Similarity: 0.95

Chemical Structure| 436095-38-4

[ 436095-38-4 ]

3-Amino-N-cyclopentylbenzenesulfonamide

Similarity: 0.95

Chemical Structure| 59724-58-2

[ 59724-58-2 ]

4-Amino-N-(sec-butyl)benzenesulfonamide

Similarity: 0.95

Chemical Structure| 77516-54-2

[ 77516-54-2 ]

N-Cyclohexyl 2-aminobenzenesulfonamide

Similarity: 0.94

Amines

Chemical Structure| 61886-26-8

[ 61886-26-8 ]

N-Cyclohexyl 3-aminobenzenesulfonamide

Similarity: 0.98

Chemical Structure| 24224-95-1

[ 24224-95-1 ]

N-(Adamantan-1-yl)-4-aminobenzenesulfonamide

Similarity: 0.95

Chemical Structure| 436095-38-4

[ 436095-38-4 ]

3-Amino-N-cyclopentylbenzenesulfonamide

Similarity: 0.95

Chemical Structure| 59724-58-2

[ 59724-58-2 ]

4-Amino-N-(sec-butyl)benzenesulfonamide

Similarity: 0.95

Chemical Structure| 77516-54-2

[ 77516-54-2 ]

N-Cyclohexyl 2-aminobenzenesulfonamide

Similarity: 0.94

Aryls

Chemical Structure| 61886-26-8

[ 61886-26-8 ]

N-Cyclohexyl 3-aminobenzenesulfonamide

Similarity: 0.98

Chemical Structure| 24224-95-1

[ 24224-95-1 ]

N-(Adamantan-1-yl)-4-aminobenzenesulfonamide

Similarity: 0.95

Chemical Structure| 436095-38-4

[ 436095-38-4 ]

3-Amino-N-cyclopentylbenzenesulfonamide

Similarity: 0.95

Chemical Structure| 59724-58-2

[ 59724-58-2 ]

4-Amino-N-(sec-butyl)benzenesulfonamide

Similarity: 0.95

Chemical Structure| 77516-54-2

[ 77516-54-2 ]

N-Cyclohexyl 2-aminobenzenesulfonamide

Similarity: 0.94