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[ CAS No. 54325-28-9 ]

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2D
Chemical Structure| 54325-28-9
Chemical Structure| 54325-28-9
Structure of 54325-28-9 *Storage: {[proInfo.prStorage]}

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Product Details of [ 54325-28-9 ]

CAS No. :54325-28-9MDL No. :MFCD00061632
Formula : C25H26O6 Boiling Point : -
Linear Structure Formula :-InChI Key :N/A
M.W :422.47Pubchem ID :54438697
Synonyms :

Computed Properties of [ 54325-28-9 ]

TPSA : 99.4 H-Bond Acceptor Count : 6
XLogP3 : 2.1 H-Bond Donor Count : 4
SP3 : 0.28 Rotatable Bond Count : 6

Safety of [ 54325-28-9 ]

Signal Word:WarningClass:N/A
Precautionary Statements:P261-P305+P351+P338UN#:N/A
Hazard Statements:H302-H315-H319-H335Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 54325-28-9 ]

  • Upstream synthesis route of [ 54325-28-9 ]
  • Downstream synthetic route of [ 54325-28-9 ]

[ 54325-28-9 ] Synthesis Path-Upstream   1~3

  • 1
  • [ 50-99-7 ]
  • [ 76-83-5 ]
  • [ 54325-28-9 ]
YieldReaction ConditionsOperation in experiment
88% at 80℃; for 4 h; To glucose (5g; 0.0277 mole) as a suspension in pyridine (50 mL) was added trityl chloride and stirred at 8O0C for about 4 hours. The completion of the reaction was checked by TLC using dichloromethane: methanol (85:15). The reaction was quenched with water (100 mL) and extracted with dichloromethane (150 ml x 2). The organic layer was washed with saturated solution of sodium bicarbonate and water, dried over anhydrous sodium sulfate and the solvent was removed by rotory evaporator. Trityl Chloride and pyridine were removed by triturating with hexane: diethyl ether mixture (10OmL) to afford the desired product (10.3 g; 88percent), LC-MS gave the M+ at 446 amu in accordance with the structure.
Reference: [1] Patent: WO2007/54977, 2007, A2, . Location in patent: Page/Page column 21
[2] Patent: KR101595939, 2016, B1, . Location in patent: Paragraph 0102-0103
  • 2
  • [ 2280-44-6 ]
  • [ 76-83-5 ]
  • [ 54325-28-9 ]
Reference: [1] Tetrahedron, 2007, vol. 63, # 40, p. 10042 - 10053
[2] Tetrahedron Letters, 1989, vol. 30, # 1, p. 35 - 38
[3] Carbohydrate Research, 1995, vol. 279, p. 281 - 291
[4] Tetrahedron Letters, 1996, vol. 37, # 23, p. 4015 - 4018
[5] Chemical and Pharmaceutical Bulletin, 1997, vol. 45, # 4, p. 626 - 630
[6] Carbohydrate Research, 1997, vol. 303, # 1, p. 1 - 15
[7] Carbohydrate Research, 1997, vol. 301, # 3-4, p. 123 - 143
[8] Journal of the American Chemical Society, 1999, vol. 121, # 51, p. 12196 - 12197
[9] Organic Letters, 2009, vol. 11, # 4, p. 939 - 942
[10] Journal of Medicinal Chemistry, 2011, vol. 54, # 5, p. 1481 - 1489
[11] Molecules, 2013, vol. 18, # 9, p. 11198 - 11218
[12] Journal of Labelled Compounds and Radiopharmaceuticals, 2014, vol. 57, # 14, p. 737 - 743
[13] Organic and Biomolecular Chemistry, 2017, vol. 15, # 23, p. 5025 - 5032
[14] Patent: CN107286207, 2017, A, . Location in patent: Paragraph 0017
  • 3
  • [ 492-62-6 ]
  • [ 76-83-5 ]
  • [ 54325-28-9 ]
Reference: [1] Patent: WO2006/115312, 2006, A1, . Location in patent: Page/Page column 20
[2] Patent: US2008/39421, 2008, A1, . Location in patent: Page/Page column 4; 8
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