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Chemical Structure| 54534-72-4 Chemical Structure| 54534-72-4

Structure of 54534-72-4

Chemical Structure| 54534-72-4

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Product Details of [ 54534-72-4 ]

CAS No. :54534-72-4
Formula : C13H7Cl2NO3
M.W : 296.11
SMILES Code : O=C(C1=CC([N+]([O-])=O)=CC=C1Cl)C2=CC=CC=C2Cl

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Application In Synthesis of [ 54534-72-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 54534-72-4 ]

[ 54534-72-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 2011-66-7 ]
  • [ 54534-72-4 ]
YieldReaction ConditionsOperation in experiment
With hydrogenchloride;copper(I) chloride; In water; acetic acid; sodium nitrite; EXAMPLE 26 (2-Chloro-5-nitrophenyl)(2-chlorophenyl)methanone To 180 ml of concentrated sulfuric acid cooled to 0 in an ice bath was added 28 g (0.4 mol) of sodium nitrite in portions at such a rate that the temperature did not go above 10. This mixture was warmed on a steam bath until a solution formed. It was then cooled to 30 and a solution of 110.68 g (0.4 mol) of <strong>[2011-66-7]2-amino-5-nitro-2'-chlorobenzophenone</strong> in 300 mL of hot acetic acid was added at such a rate that the temperature did not exceed 40. This mixture was stirred without heating for 2.5 hr, and then poured slowly into a mixture of 800 mL of concentrated hydrochloric acid and 80 g of cuprous chloride. This mixture was heated to 80 on a steam bath for 40 min until the foaming had subsided, poured into 2 l of water, and allowed to stand overnight. The solid was collected, washed with water and recrystallized from methanol to give product, mp 76-79. An analytical sample prepared by recrystallization from methanol had mp 78.5-80.
 

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