Home Cart Sign in  
Chemical Structure| 55745-83-0 Chemical Structure| 55745-83-0

Structure of 55745-83-0

Chemical Structure| 55745-83-0

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 55745-83-0 ]

CAS No. :55745-83-0
Formula : C11H13N3S
M.W : 219.31
SMILES Code : C1CN(CCN1)C1=NC2=C(S1)C=CC=C2
MDL No. :MFCD01417996
InChI Key :LLQMZXMBCQNMJV-UHFFFAOYSA-N
Pubchem ID :592122

Safety of [ 55745-83-0 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P264-P270-P301+P312-P330-P501

Application In Synthesis of [ 55745-83-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 55745-83-0 ]

[ 55745-83-0 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 182438-98-8 ]
  • [ 55745-83-0 ]
  • [ 348133-25-5 ]
YieldReaction ConditionsOperation in experiment
With potassium carbonate; In water; acetonitrile; e. 9-[4-(4-(benzothiazol-2-yl)-piperazin-1-yl)-butyl]-9H-fluorene-9-carboxylic Acid-(2,2,2-trifluoro-ethyl)-amide A suspension of 0.2 g (0.469 mmol) of <strong>[182438-98-8]9-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid-(2,2,2-trifluoro-ethyl)-amide</strong>, 0.17 g (0.775 mmol) of 2-(piperazin-1-yl)-benzothiazole, 0.1 g of potassium carbonate and 1 ml of water in 10 ml of acetonitrile is stirred for 10 hours at ambient temperature. The reaction mixture is then poured onto water, extracted with dichloromethane and the organic phase is dried over sodium sulphate. The product is purified by column chromatography on silica gel (eluant: dichloromethane/acetone =20:1, then dichloromethane/methanol=20:1). Yield: 0.16 g (60.4% of theory), Melting point: 49-52 C.
  • 2
  • [ 401564-36-1 ]
  • [ 55745-83-0 ]
  • [ 401566-38-9 ]
YieldReaction ConditionsOperation in experiment
General procedure: To a solution of 7a (450 mg, 1.50 mmol), 1-(4-chloroisoquinolin-1-yl)piperazine (446 mg, 1.80 mmol) and acetic acid (0.090 mL, 1.6 mmol) in 1,2-dichloroethane (8 mL) was added sodium triacetoxyborohydride (636 mg, 3.00 mmol) and the mixture was stirred at room temperature for 3 h. The reaction mixture was poured into a saturated aqueous sodium hydrogen carbonate solution and extracted with chloroform. The extract was washed with brine, dried and concentrated under reduced pressure. The residue purified by silica gel chromatography with chloroform/methanol (50:1, v/v) to give 3-{(2S,4S)-1-tert-butoxycarbonyl-4-[4-(4-chloroisoquinolin-1-yl)piperazin-1-yl]pyrrolidin-2-ylcarbonyl}thiazolidine (596 mg, 75%) as a white powder.The above compound (592 mg, 1.11 mmol) was dissolved in 1.1 mol/L hydrogen chloride in methanol (10 mL), and the mixture was stirred at room temperature for 5 days. The reaction mixture was concentrated under reduced pressure, and the residue was crystallized with ethanol to give the title compound (318 mg, 52%) as a pale-yellow powder.
 

Historical Records

Categories

Related Parent Nucleus of
[ 55745-83-0 ]

Piperazines

Chemical Structure| 232263-28-4

A722183 [232263-28-4]

2-(4-(Benzo[d]thiazol-2-yl)piperazin-1-yl)ethanol

Similarity: 0.93

Chemical Structure| 941869-85-8

A153121 [941869-85-8]

6-Bromo-2-(piperazin-1-yl)benzo[d]thiazole

Similarity: 0.92

Chemical Structure| 941869-85-8

A153121 [941869-85-8]

6-Bromo-2-(piperazin-1-yl)benzo[d]thiazole

Similarity: 0.92

Chemical Structure| 941869-85-8

A153121 [941869-85-8]

6-Bromo-2-(piperazin-1-yl)benzo[d]thiazole

Similarity: 0.92

Chemical Structure| 153025-29-7

A236154 [153025-29-7]

6-Chloro-2-(piperazin-1-yl)benzo[d]thiazole

Similarity: 0.90

Benzothiazoles

Chemical Structure| 24255-48-9

A302594 [24255-48-9]

N,N-Diethylbenzo[d]thiazol-2-amine

Similarity: 0.95

Chemical Structure| 108656-84-4

A324724 [108656-84-4]

N-Ethyl-N-methylbenzo[d]thiazol-2-amine

Similarity: 0.94

Chemical Structure| 612527-76-1

A289726 [612527-76-1]

N1-(Benzo[d]thiazol-2-yl)-N2,N2-dimethylethane-1,2-diamine

Similarity: 0.94

Chemical Structure| 232263-28-4

A722183 [232263-28-4]

2-(4-(Benzo[d]thiazol-2-yl)piperazin-1-yl)ethanol

Similarity: 0.93

Chemical Structure| 111628-37-6

A628170 [111628-37-6]

2-(1,4-Diazepan-1-yl)benzo[d]thiazole

Similarity: 0.93