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Chemical Structure| 5729-18-0 Chemical Structure| 5729-18-0

Structure of 5729-18-0

Chemical Structure| 5729-18-0

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Product Details of [ 5729-18-0 ]

CAS No. :5729-18-0
Formula : C13H13ClN2
M.W : 232.71
SMILES Code : NC1=CC=CC=C1NCC2=CC=C(Cl)C=C2
MDL No. :MFCD11186882

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Application In Synthesis of [ 5729-18-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 5729-18-0 ]

[ 5729-18-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 5729-18-0 ]
  • [ 1019-85-8 ]
YieldReaction ConditionsOperation in experiment
With potassium carbonate; copper(I) bromide; In dimethyl sulfoxide; at 120℃; under 760.051 Torr; for 14h; General procedure: A solutionof2-aminoaniline 4a-h (0.2 mmol), K2CO3 (0.6 mmol,83mg), andCuBr (0.02 mmol,2.8mg) in DMSO (2mL) was provided.Themixturewasallowedto stirunderair (1 atm) at 120 C for14h.Aftercompletionofthereaction,theresulting solutionwascooledtoroomtemperatureandfiltered.Afterward,thefil-trate wasevaporatedusingarotaryevaporator.Thentheresiduewaspurifiedbycol-umn chromatographyonsilicagelusingpetroleumether / ethyl acetate (3:1 to2:1) aseluent toprovide 5a-h. Alltheproductswereidentifiedandcharacterizedbycom-parison ofmeltingpoint (mp), IR,and 1H NMRand 13CNMR spectroscopy.[35]
 

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