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[ CAS No. 58609-73-7 ]

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Cat. No.: {[proInfo.prAm]}
2D
Chemical Structure| 58609-73-7
Chemical Structure| 58609-73-7
Structure of 58609-73-7 *Storage: {[proInfo.prStorage]}

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Alternatived Products of [ 58609-73-7 ]

Product Details of [ 58609-73-7 ]

CAS No. :58609-73-7MDL No. :MFCD02180706
Formula : C13H17N Boiling Point : -
Linear Structure Formula :-InChI Key :-
M.W :187.28Pubchem ID :-
Synonyms :

Computed Properties of [ 58609-73-7 ]

TPSA : - H-Bond Acceptor Count : -
XLogP3 : - H-Bond Donor Count : -
SP3 : - Rotatable Bond Count : -

Safety of [ 58609-73-7 ]

Signal Word:Class:
Precautionary Statements:UN#:
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Application In Synthesis of [ 58609-73-7 ]

  • Downstream synthetic route of [ 58609-73-7 ]

[ 58609-73-7 ] Synthesis Path-Downstream   1~6

  • 3
  • [ 3529-08-6 ]
  • [ 58609-73-7 ]
  • (R,S) 2-(4-isobutylphenyl)-N-[3-(N-piperidino)propyl]propionamidine dihydrochloride [ No CAS ]
YieldReaction ConditionsOperation in experiment
60% 2a (R, S) 2- (4-ISOBUTVLPHENYL)-N- [3- (N-PIPERIDMO) PROPVL1PROPIONAMIDINE DIHYDROCHLORIDE A solution of 2- (4-isobutylphenyl) propionitrile (0.15 g; 0.80 mmol) in a (1: 1) diethyl ether/methyl alcohol mixture (10 mL) is cooled at T =0-5C and gaseous HCl is bubbled into the solution for 1H. Then the temperature is left to arise to r. t. and the mixture stirred overnight. After solvent evaporation under reduced pressure, the crude is dissolved in methyl alcohol (10 mL) and cooled at T= 0-5 C. A solution of 3-piperidinopropylamine (0.15 g ; 0.96 mmol) in methyl alcohol (5 mL) is added dropwise and the resulting mixture is left under stirring overnight at r. t. After solvent evaporation under reduced pressure, the crude oil is suspended in 2N HCl (solution pH=2) and the product is extracted with dichloromethane (3 x 15 mL). The combined organic extracts are washed back with a saturated solution of NaCl (2 x 15 mL), dried over NA2S04 and evaporated under vacuum to give 2- (4'-isobutylphenyl)-N- [3- (N- piperidino) PROPYLPROPIONAMIDINE dihydrochloride as glassy solid (0.193 g; 0.48 mmol). Yield 60%. 1H-NMR (CDC13): 8 10. 88 (bs, NH C1 ) ; 10.22 (bs, NH+Cl-) ; 9.82 (bs, NH+Cl-); 7.64 (bs, NID ; 7.41 (d, 2H, J=8Hz) ; 7.15 (d, 2H, J=8HZ) ; 4.39 (Q, 1H, J=8HZ) ; 3.78 (m, 2H) ; 3.45 (m, 2H) ; 3.10 (m, 2H) ; 2.75 (m, 2H); 2.46 (d, 2H, J=8HZ) ; 2.32-2. 05 (m, 3H) ; 2.00-1. 68 (m, 9H) ; 0.90 (d, 6H, J=8HZ).
  • 4
  • [ 40150-92-3 ]
  • [ 58609-73-7 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: hydrogenchloride / toluene; water / 1 h 2: N-benzyl-N,N,N-triethylammonium chloride / toluene / 7 h / 100 °C
Multi-step reaction with 2 steps 1: hydrogenchloride / toluene; water / 1 h 2: N-benzyl-N,N,N-triethylammonium chloride / toluene; water; dimethyl sulfoxide / 7 h / 100 °C
  • 5
  • [ 10442-39-4 ]
  • [ 62049-65-4 ]
  • [ 40150-92-3 ]
  • [ 58609-73-7 ]
YieldReaction ConditionsOperation in experiment
1: 75% 2: 15% In acetonitrile at 100℃; Flow reactor;
  • 6
  • [ 7188-38-7 ]
  • [ 100319-40-2 ]
  • [ 58609-73-7 ]
  • N-(tert-butyl)-2-(4-isobutylphenyl)propanamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
1: 27% 2: 24% Stage #1: tert-butylisonitrile; 1-ethyl-4-(2-methylpropyl)benzene With 1,1,1,3',3',3'-hexafluoro-propanol; tetrabutylammonium p-toluenesulfonate In 1,2-dichloro-ethane at 20℃; for 4h; Electrochemical reaction; Inert atmosphere; Stage #2: With acetic acid In water monomer at 20℃; for 5h; Overall yield = 51 percent;
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