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Chemical Structure| 588720-67-6 Chemical Structure| 588720-67-6

Structure of 588720-67-6

Chemical Structure| 588720-67-6

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Product Details of [ 588720-67-6 ]

CAS No. :588720-67-6
Formula : C9H9N3O2
M.W : 191.19
SMILES Code : O=C(C1=CN2C(C=N1)=NC=C2)OCC
MDL No. :MFCD29068592

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Application In Synthesis of [ 588720-67-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 588720-67-6 ]

[ 588720-67-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 107-20-0 ]
  • [ 54013-06-8 ]
  • [ 588720-67-6 ]
YieldReaction ConditionsOperation in experiment
With sodium hydrogencarbonate; In ethanol; water; at 90℃; for 16.0h; Chloroacetaldehyde (9.5 mL of a 50 wt% solution in water) was added to a mixture of aminopyrazine (2.00 g, 12.0 mmol), sodium bicarbonate (2.00 g, 23.8 mmol) and absolute ethanol (100 mL). The reaction was heated to 90 C for 16 hours. After cooling to room temperature, the reaction was concentrated and purified by flash chromatography (silica, 0-10% methanol/chloroform) to give pure 1-1 as a tan colored solid. 1 H NMR (400 MHz, CDCI3) delta 9.18 (s, 1 H), 9.01 (d, J= 1.4, 1 H), 7.93 (d, J= 1 .1 , 1 H), 7.84 (s, 1 H), 4.51 (q, J= 7.1 , 3H), 1 .46 (t, J = 7.1 , 4H).
 

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