Home Cart Sign in  
HazMat Fee +

There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 594-45-6 Chemical Structure| 594-45-6

Structure of 594-45-6

Chemical Structure| 594-45-6

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 594-45-6 ]

CAS No. :594-45-6
Formula : C2H6O3S
M.W : 110.13
SMILES Code : CCS(=O)(O)=O
MDL No. :MFCD00007529
InChI Key :CCIVGXIOQKPBKL-UHFFFAOYSA-N
Pubchem ID :11668

Safety of [ 594-45-6 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H314
Precautionary Statements:P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338
Class:8
UN#:2586
Packing Group:

Application In Synthesis of [ 594-45-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 594-45-6 ]

[ 594-45-6 ] Synthesis Path-Downstream   1~5

  • 1
  • [ 927880-90-8 ]
  • [ 594-45-6 ]
  • {1-methyl-5-[2-(5-trifluoromethyl-1H-imidazol-2-yl)-pyridin-4-yloxy]-1H-benzoimidazol-2-yl}-(4-trifluoromethyl-phenyl)amine diesylate [ No CAS ]
YieldReaction ConditionsOperation in experiment
In tetrahydrofuran; at 20℃; for 2h; Esylate:; Two equivalents of ethanesulfonic acid were slowly added to 3g of API in 20 mL of THF at room temperature. The resulting suspension was equilibrated for two hours before solids were collected by filtration. Solids were dried under vacuum at 500C.
  • 2
  • [ 383432-38-0 ]
  • [ 594-45-6 ]
  • E-2-methoxy-N-(3-{4-[3-methyl-4-(6-methyl-pyridin-3-yloxy)-phenylamino]-quinazolin-6-yl}-allyl)-acetamide diesylate [ No CAS ]
YieldReaction ConditionsOperation in experiment
In ethanol; dichloromethane; ethyl acetate; E-2-METHOXY-N- (3- {4- [3-METHYL-4- (6-METHYL-PYRIDIN-3-YLOXY)-PHENYLAMINO]-QUINAZOLIN- 6-yl}-allyl)-acetamide free base, prepared according to the method of either Example 1,2 or 3 (3.00 grams) was dissolved in 40mL ethanol and 6mL methylene chloride. 2.05 molar equivalents of ethanesulfonic acid, dissolved in 10ML ethanol, was added to the solution of free base. The solution was concentrated and taken up in a minimal volume of ethanol, then ethyl acetate was added as an nonsolvent until precipitation occurred. The slurry was stirred at ambient temperature over 48 hours and isolated as E-2-METHOXY-N- (3- {4- [3-METHYL-4- (6- methyl-pyridin-3-yloxy)-phenylamino]-quinazolin-6-yl}-allyl)-acetamide diesylate. The diesylate complex was crystalline by PXRD. DSC showed a clean melting onset at 146C and a peak at 149. 5C. Hygroscopicity: 45% (by weight) at 90% relative humidity.
  • 3
  • [ 594-45-6 ]
  • [ 500287-72-9 ]
  • rilpivirine ethanesulfonate [ No CAS ]
YieldReaction ConditionsOperation in experiment
In tetrahydrofuran; at 45℃; Ethanesulfonic acid 95% (104 mg, 0.90 mmol, 1.1 eq) was dissolved in THF (3 mL) at room temperature and was then added dropwise to a stirred solution of <strong>[500287-72-9]Rilpivirine</strong> base form II (0.30 g, 0.82 mmol) in THF (6 mL, 20V) at 45C. Precipitation was observed. The reaction mixture was cooled to room temperature for 30 min and stirring was continued at the same temperature for 17 h. The reaction mixture was then filtered to give the title compound. The filter cake was dried in a vacuum oven at 50C for 17 h. A white solid was obtained. XRD analysis of the solid indicated the same polymorphic form as was identified in the wet material.
  • 4
  • [ 594-45-6 ]
  • [ 1227633-49-9 ]
  • 4-(2-(2-(benzo[b]thiophen-3-yl)-9-isopropyl-9H-purin-6-ylamino)ethyl)phenol esylate [ No CAS ]
YieldReaction ConditionsOperation in experiment
In acetone; at 20 - 55℃; for 18.5h; The esylate salt of SRi can be prepared as follows: 4-(2- (2-(benzo[b]thiophen-3-yl)-9-isopropyl-9H-purin-6-ylamino)ethyl)phenol free base (0.60 gram; 1.40 mmoles) are dissolved in 12 ml acetone at 50 C. Ethanesulfonic acid (0.155 gram; 1.40 mmoles) is added drop wise. The crystallization takes place quickly. The resulting white suspension is allowed to cool over about 30 minutes to room temperature. The suspension is stirred for about 18 hours at room temperature and filtered. The solid is washed with 6 ml acetone inthree portions and dried first for about 3 hours at 50 C./about5210 mbar and then for about 16 hours at 80 C./about 10 mbar.The material has a melting point at about 231 C. with amelting enthalpy of 76 g/J.In another embodiment, the i esylate salt of SRi comprisesthe following powder X-ray diffraction peaks (Angle 2-0):6.3, 9.9, 18.4, 25.3, 26.1; and which in an additional embodiment comprises the following powder X-ray diffraction peaks(Angle 2-0): 6.3, 9.9, 17.1, 17.9, 18.4, 19.0,22.0,25.3,26.1,27.1.
  • 5
  • [ 755037-03-7 ]
  • [ 594-45-6 ]
  • regorafenib ethanesulfonic acid salt [ No CAS ]
YieldReaction ConditionsOperation in experiment
In water; ethyl acetate; at 50℃; for 2h; 1.0gof <strong>[755037-03-7]Regorafenib</strong> added into 10mL of ethyl acetate and 1ml water and after heated up to reflux for clear solution added 0.23g of ethanesulfonic acid. Cooled to room temperature and stirring was continued for 2 hours after precipitation. filtered, the filter cake was wash with 1mL of ethanesulfonicacid, collected the filter cake at 50~80 C dried to constant weight for giving <strong>[755037-03-7]Regorafenib</strong> Ethanesulfonic acid salt crystal form alpha .
 

Historical Records

Technical Information

Categories

Related Functional Groups of
[ 594-45-6 ]

Aliphatic Chain Hydrocarbons

Chemical Structure| 5324-47-0

A177982 [5324-47-0]

Sodium ethanesulfonate

Similarity: 0.95

Chemical Structure| 1092929-45-7

A713435 [1092929-45-7]

1,2-Ethanedisulfonic Acid hydrate

Similarity: 0.87

Chemical Structure| 5284-66-2

A509164 [5284-66-2]

Propane-1-sulfonic acid

Similarity: 0.83

Chemical Structure| 5325-43-9

A756609 [5325-43-9]

Sodium ethane-1,2-disulfonate

Similarity: 0.83

Chemical Structure| 21668-77-9

A583529 [21668-77-9]

1,3-Propanedisulfonic Acid

Similarity: 0.80

Sulfonic Acids

Chemical Structure| 1092929-45-7

A713435 [1092929-45-7]

1,2-Ethanedisulfonic Acid hydrate

Similarity: 0.87

Chemical Structure| 5982-56-9

A921370 [5982-56-9]

Ethane-1,2-disulfonic acid dihydrate

Similarity: 0.87

Chemical Structure| 5982-56-9

A921370 [5982-56-9]

Ethane-1,2-disulfonic acid dihydrate

Similarity: 0.87

Chemical Structure| 5284-66-2

A509164 [5284-66-2]

Propane-1-sulfonic acid

Similarity: 0.83

Chemical Structure| 21668-77-9

A583529 [21668-77-9]

1,3-Propanedisulfonic Acid

Similarity: 0.80