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Chemical Structure| 83797-69-7 Chemical Structure| 83797-69-7

Structure of 6-OAU
CAS No.: 83797-69-7

Chemical Structure| 83797-69-7

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6-OAU is a surrogate agonist of GPR84 activating human GPR84 in the presence of Gqi5 chimera in HEK293 cells with an EC50 of 105 nM in the PI assay.

Synonyms: GTPL5846; 6-n-octylaminouracil

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Product Details of 6-OAU

CAS No. :83797-69-7
Formula : C12H21N3O2
M.W : 239.31
SMILES Code : O=C1NC(C=C(NCCCCCCCC)N1)=O
Synonyms :
GTPL5846; 6-n-octylaminouracil
MDL No. :MFCD28900678
InChI Key :PFSWASUQURIOOR-UHFFFAOYSA-N
Pubchem ID :10354234

Safety of 6-OAU

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Related Pathways of 6-OAU

RTK
GPCR
MAPK

Isoform Comparison

Biological Activity

Description
6-OAU (GTPL5846) (6-n-octylaminouracil) functions as a GPR84 (G protein-coupled receptor 84) agonist with an EC50 of 105 nM. It attracts PMNs and macrophages, boosts IL-8 proinflammatory cytokine levels, indicating its proinflammatory effects. Additionally, 6-OAU has antibacterial capabilities[1][2].

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