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Chemical Structure| 60421-20-7 Chemical Structure| 60421-20-7

Structure of H-Aib-OBzl·HCl
CAS No.: 60421-20-7

Chemical Structure| 60421-20-7

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Product Details of [ 60421-20-7 ]

CAS No. :60421-20-7
Formula : C11H16ClNO2
M.W : 229.70
SMILES Code : CC(C)(N)C(OCC1=CC=CC=C1)=O.[H]Cl
MDL No. :MFCD14155677
InChI Key :OXUUEIDXKLFLER-UHFFFAOYSA-N
Pubchem ID :21415531

Safety of [ 60421-20-7 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H317-H319
Precautionary Statements:P280-P305+P351+P338

Application In Synthesis of [ 60421-20-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 60421-20-7 ]

[ 60421-20-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 60421-20-7 ]
  • [ 32926-43-5 ]
  • Boc-His(Trt)-Aib-OBzl [ No CAS ]
YieldReaction ConditionsOperation in experiment
4.5 g With N-ethylmorpholine;; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; In ethyl acetate; for 4.5h; 2.5 g of Boc-L-His(Trt)-OH were suspended in 25ml of ethylacetate and 1.55 g of H-Aib-OBz1xHC1 and 2.3g of HBTU were added followed by 2.6 ml of N-ethylmorpholin. Suspension was stirred for 4.5 h. Mixture was thenextracted three times with 20 ml of a 8percent sodium bicarbonate solution followed by one wash with watet Phases were separated and the organic layer dried over sodium sulfate. After removal of the drying agent the solution was evaporated to dryness and 4.5 g of a yellow oil were obtained consisting of Boc-L-His(Trt)-Aib-OBzl with a purity of>90percent.
 

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