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Chemical Structure| 61342-04-9 Chemical Structure| 61342-04-9

Structure of 61342-04-9

Chemical Structure| 61342-04-9

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Product Details of [ 61342-04-9 ]

CAS No. :61342-04-9
Formula : C11H13F3
M.W : 202.22
SMILES Code : FC(F)(F)C1=CC=C(CCCC)C=C1
MDL No. :MFCD14525528

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Application In Synthesis of [ 61342-04-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 61342-04-9 ]

[ 61342-04-9 ] Synthesis Path-Downstream   1~4

  • 1
  • [ 20651-67-6 ]
  • [ 120120-26-5 ]
  • [ 61342-04-9 ]
  • 2
  • (1,10-phenanthroline)(trifluoromethyl)copper(I) [ No CAS ]
  • [ 20651-67-6 ]
  • [ 61342-04-9 ]
  • 3
  • [ 20651-67-6 ]
  • [ 289706-46-3 ]
  • [ 61342-04-9 ]
  • 4
  • (1,10-phenanthroline)(trifluoromethyl)copper(I) [ No CAS ]
  • [ 20651-67-6 ]
  • [ 61342-04-9 ]
YieldReaction ConditionsOperation in experiment
92%Spectr. In desipramine; benzene; at 50℃; for 12h;Inert atmosphere;Product distribution / selectivity; To a 4- mL vial equipped with a stir bar were charged 1 (7.8 mg, 0.025 mmol) or[(SIMes)2Cu][Cu(CF3)2] (1 1.0 mg, 0.025 mmol) and 4-(trifluoromethoxy)anisole in either DMF or a mixture of DMI and benzene (1 .5/7.5) (0.050 M, 0.50 mL, 0.025 mmol). To the mixture was added Arl 3b (22 mu, 0.13 mmol, 5.0 equiv), and the mixture was stirred at room temperature (for DMF; standard conditions for 1) or 50 C (forDMI/benzene; standard conditions reported by Dubinina et al.). After 1 and 18 h (for DMF) or 1 , 12 and 28 h (for DMI/benzene), the mixture was transferred to an NMR tube, and the yield of the product 4b was measured by 19F NMR analysis. The yields of the product 4b were: 19 (1 h) and 88 (18 h) % for the reaction of 1 in DMF; 0.7 (1 h) and 8.7 (18 h) % for the reaction of [(SIMes)2Cu][Cu(CF3)2] in DMF; 85 (1 h), 92 (12 h) and 91 (28 h) % for the reaction of 1 in DMI/benzene; 8.3 (1 h), 53 (12 h) and 70 (28 h) % for the reaction of [(SIMes)2Cu][Cu(CF3)2] in DMI/benzene
 

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