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Chemical Structure| 616195-94-9 Chemical Structure| 616195-94-9

Structure of 616195-94-9

Chemical Structure| 616195-94-9

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Product Details of [ 616195-94-9 ]

CAS No. :616195-94-9
Formula : C16H26Cl2OSi
M.W : 333.37
SMILES Code : CC([Si](C(C)C)(OCC1=CC(Cl)=CC(Cl)=C1)C(C)C)C

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Application In Synthesis of [ 616195-94-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 616195-94-9 ]

[ 616195-94-9 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 60211-57-6 ]
  • [ 80522-42-5 ]
  • [ 616195-94-9 ]
YieldReaction ConditionsOperation in experiment
79% With 2,6-dimethylpyridine; In dichloromethane; at 0℃; for 2h; To a solution of <strong>[60211-57-6](3,5-dichlorophenyl)methanol</strong> (10.0 g, 56.5 mmol) in methylene chloride (100 mL) at 0 0C was added 2,6-lutidine (16.4 mL, 141 mmol) followed by triisopropylsilyl triflate (19.7 mL, 73.4 mmol), and was stirred at 0 0C for 2 hours. The reaction was diluted with water and the organic layer was separated, washed with brine, dried over Na2SO4, filtered and concentrated. The residue was purified by chromatography on silica gel, eluting with hexane to provide the desired product (14.8 g, 79%). LC/MS: 333 (M+H)+, 1H NMR (CDCl3) delta 7.23 (s, 3H), 4.78 (s, 2H), 1.18 (m, 3H), 1.03 (s, 18H).
 

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