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Structure of Cyclobenzaprine HCI
CAS No.: 6202-23-9
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The BI-3802 was designed by Boehringer Ingelheim and could be obtained free of charge through the Boehringer Ingelheim open innovation portal opnMe.com, associated with its negative control.
Cyclobenzaprine HCl is a 5-HT2 receptor antagonist as a skeletal muscle relaxant and a central nervous system (CNS) depressant with elimination half-life of 32 hours.
Synonyms: MK130 hydrochloride; Cyclobenzaprine(hydrochloride)(CRM); MK-130
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Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
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CAS No. : | 6202-23-9 |
Formula : | C20H22ClN |
M.W : | 311.85 |
SMILES Code : | CN(CCC=C1C2=C(C=CC3=C1C=CC=C3)C=CC=C2)C.[H]Cl |
Synonyms : |
MK130 hydrochloride; Cyclobenzaprine(hydrochloride)(CRM); MK-130
|
MDL No. : | MFCD00079039 |
InChI Key : | VXEAYBOGHINOKW-UHFFFAOYSA-N |
Pubchem ID : | 22576 |
GHS Pictogram: |
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Signal Word: | Danger |
Hazard Statements: | H301-H312+H332 |
Precautionary Statements: | P280-P301+P310 |
Class: | 6.1 |
UN#: | 2811 |
Packing Group: | Ⅲ |
Target |
|
Clinical Trial:
NCT Number | Conditions | Phases | Recruitment | Completion Date | Locations |
NCT02891759 | Breast Cancer | Phase 2 | Recruiting | April 30, 2020 | United States, Missouri ... More >> Washington University School of Medicine Recruiting Saint Louis, Missouri, United States, 63110 Contact: Terence M Myckatyn, M.D. 314-996-8800 myckatyn@wustl.edu Principal Investigator: Terence M Myckatyn, M.D. Sub-Investigator: Marissa Tenenbaum, M.D. Sub-Investigator: Julie Margenthaler, M.D. Sub-Investigator: Amy Cyr, M.D. Sub-Investigator: Raj Parikh, M.D. Sub-Investigator: Elizabeth B Odom, M.D. Less << |
NCT00386243 | Low Back Pain ... More >> Pain Pain, Intractable Less << | Not Applicable | Completed | - | United States, Indiana ... More >> Richard Roudebush VA Medical Center, Indianapolis Indianapolis, Indiana, United States, 46202-2884 Less << |
NCT02651324 | Idiopathic Scoliosis ... More >> Post-operative Pain Less << | Phase 4 | Active, not recruiting | December 2017 | United States, New York ... More >> Albany Medical Center Albany, New York, United States, 12208 Less << |
NCT02707094 | Chronic Low Back Pain | Not Applicable | Completed | - | United States, Texas ... More >> Brooke Army Medical Center Fort Sam Houston, Texas, United States, 78234 Less << |
NCT02202369 | Single Level Lumbar Decompress... More >>ion and Fusion Spine Surgery Less << | Phase 4 | Recruiting | March 2022 | United States, North Carolina ... More >> OrthoCarolina Recruiting Charlotte, North Carolina, United States, 28207 Contact: Susan M Odum, PhD 704-323-2265 Susan.Odum@OrthoCarolina.com Contact: Christi Cadd, MBA 704.323.2260 christi.cadd@orthocarolina.com Sub-Investigator: Bruce Darden, MD Sub-Investigator: Eric Laxer, MD Principal Investigator: Alden Milam, MD Sub-Investigator: Alfred Rhyne, MD Sub-Investigator: Bradley Segebarth, MD Sub-Investigator: Leo Spector, MD Less << |
NCT00386243 | - | Completed | - | - | |
NCT03508700 | PTSD | Phase 3 | Enrolling by invitation | September 2019 | United States, Arkansas ... More >> Little Rock Little Rock, Arkansas, United States, 72211 United States, California Beverly Hills Beverly Hills, California, United States, 90210 Oceanside Oceanside, California, United States, 92056 Orange Orange, California, United States, 92868 Temecula Temecula, California, United States, 92591 United States, Colorado Colorado Springs Colorado Springs, Colorado, United States, 80910 United States, Connecticut Norwich Norwich, Connecticut, United States, 06360 United States, Florida Tampa Tampa, Florida, United States, 33609 United States, Georgia Atlanta Atlanta, Georgia, United States, 30341 United States, Massachusetts New Bedford New Bedford, Massachusetts, United States, 02740 United States, Nevada Las Vegas Las Vegas, Nevada, United States, 89102 United States, New York Cedarhurst Cedarhurst, New York, United States, 11516 New York New York, New York, United States, 10128 United States, Ohio Canton Canton, Ohio, United States, 44718 Cincinnati Cincinnati, Ohio, United States, 45219 United States, Oklahoma Oklahoma City Oklahoma City, Oklahoma, United States, 73103 Less << |
NCT02277704 | PTSD | Phase 2 | Completed | - | - |
NCT03207828 | Fibromyalgia ... More >>Depression Less << | Not Applicable | Recruiting | May 31, 2019 | Chile ... More >> Red Salud UC Christus Recruiting Santiago, Chile, Macul Contact: Josefina Durán, MA jgduran@uc.cl Contact: Matías González, PhD magonza@med.puc.cl Less << |
NCT01028014 | Urethral Sphincter Activity | Not Applicable | Completed | - | United States, Alabama ... More >> University of Alabama at Birmingham, The Kirklin Clinic Birmingham, Alabama, United States, 35233 Less << |
NCT02436096 | Fibromyalgia ... More >>Myofascial Pain Syndromes Muscular Diseases Musculoskeletal Diseases Nervous System Diseases Neuromuscular Diseases Rheumatic Diseases Less << | Phase 3 | Completed | - | - |
NCT02403687 | - | Completed | - | - | |
NCT02015234 | Primary Fibromyalgia | Phase 3 | Completed | - | United States, Colorado ... More >> Denver Denver, Colorado, United States, 80239 United States, Florida 16176 Cortez Boulevard Brooksville, Florida, United States, 34601 100 West Gore Street Orlando, Florida, United States, 32806 United States, Maryland 71 Thomas Johnson Drive Frederick, Maryland, United States, 21702 United States, Massachusetts 370 Faunce Corner Road North Dartmouth, Massachusetts, United States, 02747 Worcester Worcester, Massachusetts, United States, 01605 United States, Mississippi Jackson Jackson, Mississippi, United States, 39202 United States, Ohio Cincinnati Cincinnati, Ohio, United States, 45219 1275 Olentangy River Road Columbus, Ohio, United States, 43212 18660 Bagley Road Middleburg Heights, Ohio, United States, 44130 United States, Pennsylvania 1001 South Market Street Mechanicsburg, Pennsylvania, United States, 17055 United States, South Carolina 322 Memorial Drive Greer, South Carolina, United States, 29650 United States, Washington 601 Broadway Seattle, Washington, United States, 98122 Less << |
NCT01028014 | - | Completed | - | - | |
NCT03110575 | PTSD | Phase 3 | Terminated(Stopped early due t... More >>o inadequate separation on primary efficacy endpoint in the lead-in HONOR study, TNX-CY-P301) Less << | - | - |
NCT02015234 | - | Completed | - | - | |
NCT02974166 | Temporomandibular Disorder | Not Applicable | Completed | - | Brazil ... More >> Brazilian Institute of Osteopathy Porto Alegre, Rio Grande do Sul, Brazil Less << |
NCT01587274 | Acute Low Back Pain | Phase 4 | Completed | - | United States, New York ... More >> Montefiore Medical Center Bronx, New York, United States, 10467 Less << |
NCT01587274 | - | Completed | - | - | |
NCT02589275 | Primary Fibromyalgia | Phase 3 | Terminated(For business reason... More >> unrelated to safety or tolerability,Tonix has discontinued the Fibromyalgia development with TNX102 SL.) Less << | - | - |
NCT01903265 | - | Completed | - | - | |
NCT02421679 | PTSD | Phase 2 | Completed | - | United States, Alabama ... More >> Tuscaloosa VA Medical Center Tuscaloosa, Alabama, United States, 35404 United States, Arizona Noesis Pharma Phoenix, Arizona, United States, 85032 United States, California Sun Valley Reserach Center Imperial, California, United States, 92251 Synergy Clinical Research National City, California, United States, 91950 Excell Research, Inc Oceanside, California, United States, 92506 Neuropsychiatric Research Center of Orange County Orange, California, United States, 92868 CITRIALS Riverside, California, United States, 92506 CESAMH San Diego, California, United States, 92103 Cns, Inc. Torrance, California, United States, 90502 United States, Florida Sarkis Clinical Trials Lake City, Florida, United States, 32025 Compass Research North, LLC Leesburg, Florida, United States, 34748 Clinical Neuroscience Solutions, Inc. Orlando, Florida, United States, 32801 United States, Georgia Atlanta Center For Medical Research Atlanta, Georgia, United States, 30308 United States, Illinois Great Lakes Clinical Trials Chicago, Illinois, United States, 60640 United States, Massachusetts Novex Clinical Research New Bedford, Massachusetts, United States, 02740 United States, Nebraska Premier Psychiatric Research Instititute, Inc. Lincoln, Nebraska, United States, 68526 United States, Nevada Altea Research Las Vegas, Nevada, United States, 89102 United States, New York Neurobehavioral Research, Inc. Cedarhurst, New York, United States, 11516 United States, Ohio University of Cincinnati College of Medicine Cincinnati, Ohio, United States, 45219 University Hospitals Case Medical Center Cleveland, Ohio, United States, 44106 United States, Texas Clinical Trials of Texas San Antonio, Texas, United States, 78229 United States, Washington Northwest Clinical Research Center Bellevue, Washington, United States, 98007 Less << |
NCT02497066 | Pain | Phase 3 | Enrolling by invitation | January 2019 | - |
NCT00635037 | Myofascial Pain Syndromes | Not Applicable | Completed | - | Brazil ... More >> Pain Setor of Federal University of Sao Paulo Sao Paulo, SP, Brazil Less << |
NCT02829814 | Fibromyalgia ... More >>Myofascial Pain Syndromes Muscular Diseases Nervous System Diseases Neuromuscular Diseases Rheumatic Diseases Musculoskeletal Diseases Less << | Phase 3 | Terminated(For business reason... More >> unrelated to safety or tolerability,Tonix has discontinued the Fibromyalgia development with TNX102 SL.) Less << | - | - |
NCT01903265 | Primary Fibromyalgia | Phase 2 Phase 3 | Completed | - | United States, California ... More >> 107 Scripps Drive Sacramento, California, United States, 95825 United States, Colorado Radiant Research, Inc. Denver, Colorado, United States, 80239 United States, Florida 16176 Cortez Boulevard Brooksville, Florida, United States, 34601 100 West Gore Street Orlando, Florida, United States, 32806 United States, Illinois 3401 North Central Avenue Chicago, Illinois, United States, 60634 United States, Maryland 71 Thomas Johnson Drive Frederick, Maryland, United States, 21702 United States, Massachusetts 370 Faunce Corner Road North Dartmouth, Massachusetts, United States, 02747 Clinical Pharmacology Study Group Worcester, Massachusetts, United States, 01605 United States, Mississippi CRC of Jackson, LLC Jackson, Mississippi, United States, 39202 United States, Ohio University of Cincinnati College of Medicine Cincinnati, Ohio, United States, 45219 1275 Olentangy River Road Columbus, Ohio, United States, 43212 18660 Bagley Road Middleburg Heights, Ohio, United States, 44130 United States, Pennsylvania 1001 South Market Street Mechanicsburg, Pennsylvania, United States, 17055 United States, South Carolina 322 Memorial Drive Greer, South Carolina, United States, 29650 United States, Utah 1002 E. South Temple Salt Lake City, Utah, United States, 84102 United States, Washington 1951 152nd Place NE Bellevue, Washington, United States, 98007 601 Broadway Seattle, Washington, United States, 98122 Less << |
NCT03127592 | Pain, Acute | Phase 3 | Not yet recruiting | December 18, 2018 | - |
NCT01421433 | Low Back Pain | Phase 3 | Unknown | January 2013 | Brazil ... More >> Hospital São Luiz Not yet recruiting São Paulo, Brazil, 05673-050 Contact: Rogerio T. Silva 551181716767 rogerio@neo.org.br Less << |
NCT02862977 | Musculoskeletal Pain | Phase 3 | Not yet recruiting | June 29, 2018 | - |
NCT03025113 | Musculoskeletal Pain | Phase 3 | Not yet recruiting | January 30, 2019 | - |
NCT03062540 | PTSD | Phase 3 | Terminated(Stopped early due t... More >>o inadequate separation on primary efficacy endpoint at Week 12 according to Interim Analysis conducted on the first 274 (50%) patients.) Less << | - | - |
NCT03168022 | Healthy Adults | Phase 1 | Completed | - | Canada ... More >> InVentiv Health Clinique Inc. Quebec, Canada, GIP )A2 Less << |
NCT01689259 | Healthy Adults | Phase 1 | Completed | - | Canada, Quebec ... More >> PharmaNet, Inc. Quebec City, Quebec, Canada, G1P 0A2 Less << |
NCT01889173 | Healthy Adults | Phase 1 | Completed | - | Canada, Quebec ... More >> PharmaNet, Inc. Quebec City, Quebec, Canada, G1P 0A2 Less << |
NCT01587508 | Acute Lumbago | Phase 3 | Withdrawn(The comparator produ... More >>ct was withdrawn from the brazilian market not being possible to conduct the design regarding initially planned.) Less << | - | Brazil ... More >> Clínica de Ortopedia e Fraturas de Goiânia Goiania, GO, Brazil CIP Pesquisas Médicas Ltda Goiânia -, GO, Brazil Santa Casa de Misericórdia de Belo Horizonte Belo Horizonte, MG, Brazil Santa Casa de Juíz de Fora Juiz de Fora, MG, Brazil Hospital de Clínicas de Porto Alegre Porto Alegre, RS, Brazil Faculdade de Medicina ABC Santo Andre,, SP, Brazil Clinica de Ortopedia e Fisiatria Perdizes São Paulo, SP, Brazil Hospital Santa Marcelina São Paulo, SP, Brazil IMA Brasil São Paulo, SP, Brazil Santa Casa de Votuporanga Votuporanga, SP, Brazil Hospítal de Base São José Rio Preto, São Paulo, Brazil Less << |
NCT00790270 | - | Completed | - | - | |
NCT00913419 | Depression | Phase 1 | Completed | - | - |
NCT01490788 | Healthy | Phase 1 | Completed | - | Canada, Quebec ... More >> PharmaNet, Inc. Québec City, Quebec, Canada, G1P 0A2 Less << |
NCT01634412 | Healthy Adults | Phase 1 | Completed | - | Canada, Quebec ... More >> PharmaNet, Inc. Quebec City, Quebec, Canada, G1P 0A2 Less << |
NCT01081990 | Postoperative Pain | Not Applicable | Unknown | December 2013 | United States, Illinois ... More >> Evanston NorthShore University HealthSystem Recruiting Evanston, Illinois, United States, 60201 Contact: Manhan K Vu, DO 847-570-2750 Principal Investigator: Manhan K Vu, DO Less << |
NCT01490788 | - | Completed | - | - | |
NCT00246389 | Pain Spasm | Phase 4 | Completed | - | - |
NCT01041495 | Fibromyalgia ... More >>Pain Sleep Fatigue Less << | Phase 4 | Unknown | March 2013 | United States, New York ... More >> SUNY Upstate Medical University Recruiting Syracuse, New York, United States, 13210 Contact: thomas l schwartz, md 315-464-3166 schwartt@upstate.edu Principal Investigator: Thomas L Schwartz, MD Less << |
NCT02814565 | Neck Pain Bac... More >>k Pain Spasm Less << | Phase 3 | Completed | - | Russian Federation ... More >> Lipetsk, Lipetsk region, Russian Federation Saransk, Republic of Mordovia, Russian Federation Kazan, Republic of Tatarstan, Russian Federation Ekaterinburg, Sverdlovsk region, Russian Federation Moscow, Russian Federation Nizhny Novgorod, Russian Federation Novosibirsk, Russian Federation Saint-Petersburg, Russian Federation Tver, Russian Federation Yaroslavl, Russian Federation Less << |
NCT03353922 | Driving Impaired | Phase 1 | Completed | - | United States, California ... More >> Collaborative Neuroscience Network Long Beach, California, United States, 92845 United States, Georgia NeuroTrials Research Atlanta, Georgia, United States, 30342 Less << |
NCT01151787 | Chronic Migraine | Phase 3 | Terminated(Study was never ini... More >>tiated under new location/provider group. Contract to continue was never signed between TEVA and Kennedy Headache Center) Less << | - | United States, New Jersey ... More >> The Headache Center at Kennedy Health Alliance Cherry Hill, New Jersey, United States, 08002 Less << |
NCT02642861 | Liver Cirrhosis | Phase 3 | Not yet recruiting | December 2019 | Egypt ... More >> Tanta university - faculty of medicine Tanta, Egypt Less << |
NCT01921296 | Sleep Initiation and Maintenan... More >>ce Disorders Pain Less << | Phase 2 | Terminated(Accrual terminated ... More >>early because of poor accrual) Less << | - | United States, Michigan ... More >> University of Michigan Comprehensive Cancer Center Ann Arbor, Michigan, United States, 48109-0944 Less << |
NCT00778037 | Healthy | Not Applicable | Completed | - | India ... More >> Ranbaxy CPU Gurgaon, Haryana, India Less << |
NCT03443960 | Healthy Subjects | Phase 1 | Completed | - | Canada, Quebec ... More >> Quebec City Quebec City, Quebec, Canada, G1P 0A2 Less << |
NCT00790270 | Cervical Strain | Phase 2 | Completed | - | United States, New York ... More >> Stony Brook University Stony Brook, New York, United States, 11733 Less << |
NCT01921296 | - | Terminated(Accrual terminated ... More >>early because of poor accrual) Less << | - | - |
Bio Calculators | ||||
Preparing Stock Solutions | ![]() |
1mg | 5mg | 10mg |
1 mM 5 mM 10 mM |
3.21mL 0.64mL 0.32mL |
16.03mL 3.21mL 1.60mL |
32.07mL 6.41mL 3.21mL |