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Chemical Structure| 620533-92-8 Chemical Structure| 620533-92-8

Structure of 620533-92-8

Chemical Structure| 620533-92-8

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Product Details of [ 620533-92-8 ]

CAS No. :620533-92-8
Formula : C9H5F6N3
M.W : 269.15
SMILES Code : FC(C1=CC(C(F)(F)F)=CC(CN=[N+]=[N-])=C1)(F)F

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Application In Synthesis of [ 620533-92-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 620533-92-8 ]

[ 620533-92-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 32707-89-4 ]
  • [ 620533-92-8 ]
YieldReaction ConditionsOperation in experiment
70% With diphenyl phosphoryl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; at 0 - 20℃; for 22h; The title compound was synthesized according to a procedure by Hamilton.53,5-Trifluoromethylphenylmethanol (2.50 g, 10.2 mmol) in THF (50 mL) was cooled to 0 oC, and added DBU (1.68 mL, 11.3 mmol, 1.1 eq) and DPPA (3.10 g, 11.3 mmol, 1.1 eq). The reaction was then allowed to reach room temperature and stirred for 22 hrs. The crude mixture was then evaporated to dryness and purified using flash column chromatography (100% pentane), affording 5d as a lightly colored oil (2.04 g, 7.2 mmol, 70%). 1H NMR data was in accordance with previously reported spectra for this compound.61H NMR (400 MHz, CDCl3): 7.86 (s, 1H, HAr-4), 7.79 (s, 2H, HAr-2 and HAr-6), 4.55 (s, 2H, CH2) ppm.
 

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