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Chemical Structure| 628329-62-4 Chemical Structure| 628329-62-4

Structure of 628329-62-4

Chemical Structure| 628329-62-4

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Product Details of [ 628329-62-4 ]

CAS No. :628329-62-4
Formula : C13H14N2O3
M.W : 246.26
SMILES Code : O=C(C1=CC(OCC2=CC=CC=C2)=NN1C)OC
MDL No. :MFCD25541576

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Application In Synthesis of [ 628329-62-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 628329-62-4 ]

[ 628329-62-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 100-39-0 ]
  • [ 52867-42-2 ]
  • [ 628329-62-4 ]
YieldReaction ConditionsOperation in experiment
96% With potassium carbonate; In DMF (N,N-dimethyl-formamide); at 20℃; for 2h; Reference Example 11 A mixture of methyl3-hydroxy-l-methyl-lH-pyrazole-5- carboxylate (1.45 g), benzyl bromide (1.16 ml), potassium carbonate (1.54 g) and N, N-dimethylformamide (10 ml) was stirred at room temperature for 2 hours. The reaction mixture was poured into dilute hydrochloric acid, and extracted with ethyl acetate. The ethyl acetate layer was washed with saturated aqueous sodium chloride solution, dried(MgS04) and concentrated. The residue was subjected to silica gel column chromatography, and methyl3-benzyloxy-1-methyl-lH-pyrazole-5- carboxylate (2.20 g, yield96%) was obtained as a colorless <Desc/Clms Page number 124>oil from a fraction eluted with ethyl acetate-hexane (1: 5, volume ratio). H-NMR (CDC13) 6 : 3.86 (3H, s), 4.05 (3H, s), 5.19 (2H, s), 6.21 (1H, s), 7.27-7. 50 (5H, m).
 

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