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Chemical Structure| 6342-64-9 Chemical Structure| 6342-64-9

Structure of 6342-64-9

Chemical Structure| 6342-64-9

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Product Details of [ 6342-64-9 ]

CAS No. :6342-64-9
Formula : C9H9ClO2
M.W : 184.62
SMILES Code : CC(C1=CC(Cl)=CC=C1OC)=O
MDL No. :MFCD00174339
InChI Key :QPIUQLBBCQTWMJ-UHFFFAOYSA-N
Pubchem ID :240434

Safety of [ 6342-64-9 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P301+P312-P302+P352-P304+P340-P305+P351+P338

Application In Synthesis of [ 6342-64-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 6342-64-9 ]

[ 6342-64-9 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 6342-64-9 ]
  • [ 35253-21-5 ]
YieldReaction ConditionsOperation in experiment
40% 1 -(5-Chloro-2-methoxyphenyl)ethanamine:; l-(5-Chloro-2-methoxyphenyl)ethanone (6.7 g, 36.3 mmol) and formic acid (1.74 g, 27.7 mmol) were heated in formamide (10 mL) at 170 0C for 20 h. The mixture was cooled to EPO <DP n="51"/>room temperature, diluted with water and extracted with benzene. After removal of benzene by rotary evaporation the crude mixture was heated under reflux conditions in 3 M HCl for 3O h. After cooling, the reaction was added to ether and extracted. The aqueous layer was basified with NaOH to pH 9 and extracted with dichloromethane. The dichloromethane was evaporated to collect the title compound (2.7 g, 40 %). 1H NMR (400 MHz, CDC13): δ 7.39 (d, IH), 7.26 (q, IH), 6.81 (d, IH), 4.62 (m, IH), 3.84 (s, 3H), 1.69 (d, 3H).
  • 2
  • [ 55877-79-7 ]
  • [ 75-16-1 ]
  • [ 6342-64-9 ]
 

Historical Records

Technical Information

• Alkyl Halide Occurrence • Baeyer-Villiger Oxidation • Barbier Coupling Reaction • Baylis-Hillman Reaction • Benzylic Oxidation • Birch Reduction • Blanc Chloromethylation • Bucherer-Bergs Reaction • Clemmensen Reduction • Corey-Bakshi-Shibata (CBS) Reduction • Corey-Chaykovsky Reaction • Fischer Indole Synthesis • Friedel-Crafts Reaction • General Reactivity • Grignard Reaction • Henry Nitroaldol Reaction • Hiyama Cross-Coupling Reaction • Horner-Wadsworth-Emmons Reaction • Hydride Reductions • Hydrogenolysis of Benzyl Ether • Kinetics of Alkyl Halides • Kumada Cross-Coupling Reaction • Lawesson's Reagent • Leuckart-Wallach Reaction • McMurry Coupling • Meerwein-Ponndorf-Verley Reduction • Nomenclature of Ethers • Passerini Reaction • Paternò-Büchi Reaction • Petasis Reaction • Peterson Olefination • Pictet-Spengler Tetrahydroisoquinoline Synthesis • Preparation of Aldehydes and Ketones • Preparation of Alkylbenzene • Preparation of Amines • Preparation of Ethers • Prins Reaction • Reactions of Aldehydes and Ketones • Reactions of Alkyl Halides with Reducing Metals • Reactions of Amines • Reactions of Benzene and Substituted Benzenes • Reactions of Ethers • Reformatsky Reaction • Robinson Annulation • Schlosser Modification of the Wittig Reaction • Schmidt Reaction • Specialized Acylation Reagents-Ketenes • Stille Coupling • Stobbe Condensation • Substitution and Elimination Reactions of Alkyl Halides • Suzuki Coupling • Tebbe Olefination • Ugi Reaction • Vilsmeier-Haack Reaction • Wittig Reaction • Wolff-Kishner Reduction

Categories

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