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Chemical Structure| 64917-81-3 Chemical Structure| 64917-81-3

Structure of 64917-81-3

Chemical Structure| 64917-81-3

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Product Details of [ 64917-81-3 ]

CAS No. :64917-81-3
Formula : C7H7ClO2
M.W : 158.58
SMILES Code : OC1=CC(Cl)=CC=C1CO
MDL No. :MFCD11042786

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Application In Synthesis of [ 64917-81-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 64917-81-3 ]

[ 64917-81-3 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 22717-55-1 ]
  • [ 64917-81-3 ]
  • 2
  • ether-AcOEt [ No CAS ]
  • hexane-AcOEt [ No CAS ]
  • [ 22717-55-1 ]
  • [ 64917-81-3 ]
YieldReaction ConditionsOperation in experiment
In tetrahydrofuran; water; argon; REFERENCE EXAMPLE 47 2-Hydroxymethyl-5-chlorophenol To a solution of lithium aluminum hydride (1.1 g) in THF (50 ml), <strong>[22717-55-1]methyl 4-chloro-2-hydroxybenzoate</strong> (5.38 g; prepared in Reference Example 46.) in THF (50 ml) was added dropwise in a stream of argon at 0 C. After the solution was warmed to at room temperature, the solution was stirred for 30 minutes. To the reaction mixture, water was added. The mixture was extracted with mixture solution of ether-AcOEt, washed, dried over and concentrated under the reduced pressure. The residue was recrystallized from mixture solution of hexane-AcOEt to give the title compound (3.92 g) having the following physical data. TLC: Rf 0.60 (hexane:AcOEt=1:1).
 

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