Alternatived Products of [ 652981-44-7 ]
Product Details of [ 652981-44-7 ]
CAS No. : | 652981-44-7 |
MDL No. : | |
Formula : |
C11H16N2O4S
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Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
272.32
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Pubchem ID : | - |
Synonyms : |
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Safety of [ 652981-44-7 ]
Signal Word: | |
Class: | |
Precautionary Statements: | |
UN#: | |
Hazard Statements: | |
Packing Group: | |
Application In Synthesis of [ 652981-44-7 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 652981-44-7 ]
- 1
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[ 259654-73-4 ]
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[ 24424-99-5 ]
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[ 652981-44-7 ]
Yield | Reaction Conditions | Operation in experiment |
60% |
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To a solution of the compound prepared in Step 2 (5.00 g, 26.8 [MMOL)] and DMAP (32 mg, 0.26 [MMOL)] in [CH2C12] (150 mL) was added BOC2O (7.00 g, 32.2 [MMOL).] After 4 h, additional quantities of [BOC20] (7.00 g, 32.2 [MMOL)] and Et3N (7.50 mL, 53.6 [MMOL)] were added. The reaction mixture was stirred at rt for 18 h, then a saturated solution of [NH4CI] (100 mL) was added and the reaction was stirred for 15 minutes. The layers were separated, dried [(NA2SO4),] filtered, and concentrated under reduced pressure. The residue was passed through a short plug of silica gel to yield a mixture of the corresponding mono-and di-carbamate. This mixture was dissolved in [MEOH] (40 mL), and a [1 N SOLUTION] of [NAOH] (20 mL) was added. The solution was stirred for 90 minutes, the methanol removed under reduced pressure and the residue was washed with [ET20] (2 x 10 mL). The aqueous layer was acidified to [PH # 4 ] using 1 N HCI, extracted with CH2CI2 (2 x 50 mL), and the combined organic layers dried [(NA2SO4),] filtered and concentrated under reduced pressure to afford the desired product as a yellow solid (4. [4 G,] 60%). (C11H16N2O4S) : LC-MS, [RT 2.] 39 min, (M+H) [+ 272.] 9 ;'H NMR [(CDCI3)] : [6] 1.51 (s, 9H), 2.32 (s, 3H), [3.] 61 (s, 2H). |
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