Alternatived Products of [ 660440-57-3 ]
Product Details of [ 660440-57-3 ]
CAS No. : | 660440-57-3 |
MDL No. : | MFCD04115652 |
Formula : |
C11H15BO4
|
Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | PRCOGZNDLWXGHB-UHFFFAOYSA-N |
M.W : |
222.05
|
Pubchem ID : | 3851700 |
Synonyms : |
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Safety of [ 660440-57-3 ]
Application In Synthesis of [ 660440-57-3 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 660440-57-3 ]
- 1
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[ 660440-57-3 ]
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[ 166316-48-9 ]
Yield | Reaction Conditions | Operation in experiment |
72% |
With sodium hydroxide for 3h; Heating; |
|
- 2
-
[ 40640-98-0 ]
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[ 660440-57-3 ]
- 3
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[ 64-17-5 ]
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[ 166316-48-9 ]
-
[ 660440-57-3 ]
Yield | Reaction Conditions | Operation in experiment |
|
With hydrogenchloride for 24h; Heating / reflux; |
P20 Preparation 20; [4- [2-ETHOXYCARBONYLETHYL] PHENYLBORONIC] acid (P20)
4- (2-Carboxyethyl) phenylboronic acid (4 [G,] 20.6 [MMOL)] was stirred at reflux for 24 hours in [ETHANOLIC] hydrochloric acid. The reaction mixture was cooled, then concentrated to afford the title compound as an oil. |
- 4
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[ 660440-56-2 ]
-
[ 660440-57-3 ]
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[ 660440-52-8 ]
Yield | Reaction Conditions | Operation in experiment |
|
With pyridine; N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 4h; |
P24 Preparation 24; [3- {4- [3- (4-NITROPHENYL)-2-OXO-2H-PYRIDIN-1-YL] PHENYL) PROPIONIC] acid ethyl ester (P24)
[3- (4-NITROPHENYL)-1H-PYRIDIN-2-ONE] (P3) (0.2 [G,] 0.92 [MMOL),] copper [(II)] acetate (0.334 [G,] 2 equiv. ), diisopropylethylamine (0.31 mL, 2 equiv. ), and pyridine (0.15 mL, 2 equiv. ) were added to a stirred solution of 4- (2-ethoxycarbonylethyl) phenyl boronic acid (0.308 g, 1.3 [MMOL)] in dichloromethane (10 mL). The reaction mixture was then stirred under argon at room temperature for 4 hours. The solution was then filtered through celite, concentrated and purified by chromatography on silica gel (50% v/v ethyl acetate in hexane) to afford the title compound as an oil. MS (ES+ve): [M+H] [+] at [M/Z] 393 [(C22H2ON205] requires [M+H] [+ AT M/Z] 393). |
- 5
-
[ 660440-57-3 ]
-
[ 850568-48-8 ]
Yield | Reaction Conditions | Operation in experiment |
70% |
With diisobutylaluminium hydride In tetrahydrofuran; toluene at -78 - 20℃; Inert atmosphere; |
|
- 6
-
[ 102854-88-6 ]
-
[ 660440-57-3 ]
-
[ 850568-48-8 ]
Yield | Reaction Conditions | Operation in experiment |
70% |
In tetrahydrofuran reaction with aluminium hydride at -78 to 0 °C followed by reaction with Rochelle's salt for 12 h at 0 °C to room temp.; one phase-switch purification used; |
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